Peptide Impurity 81 TFA CAS CATO-CPTD788581
| CAS No. | CATO-CPTD788581 |
| Molecular Formula | C18H20N2O5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Peptide Impurity 81 TFA.
CATO supplies Peptide Impurity 81 TFA (CAS CATO-CPTD788581), a pharmacopoeial impurity reference standard (molecular formula C18H20N2O5C2HF3O2, MW 458.39 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Peptide Impurity 81 TFA is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 458.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Peptide Impurity 81 TFA meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H20N2O5 C2HF3O2 |
| Molecular Weight | 458.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Peptide Standards
- Tau Peptide (306-317) trifluoroacetate salt (CAS 1003007-59-7)
- Peptide Impurity 82 (CAS 10491-78-8)
- Peptide T (CAS 106362-32-7)
- Peptide WE-14 (CAS 115136-18-0)
- Peptide YY (human) trifluoroacetate salt (CAS 118997-30-1)
- Peptide Impurity 15 (CAS 1227750-69-7)
- Peptide YY (3-36) (human) (CAS 123583-37-9)
- Tau Peptide (379-408) trifluoroacetate salt (CAS 1246357-53-8)
Recommended Standards
- Relugolix Impurity 81 (CAS CATO-C4X-242981)
- Mesalazine EP Impurity N (CAS 96-97-9)
- Oxiracetam Impurity 17 (CAS 25747-41-5)
- tert-Butyl 4-(cyanomethyl)-3-oxopiperazine-1-carboxylate (CAS 234108-59-9)
- 5-Isobutoxy-1-isobutyl-1H-pyrazole-4-carboxylic acid (CAS 1437454-43-7)
- Tert-butyl ((4-cyano-5-methoxypyridin-3-yl)methyl)carbamate (CAS 1142191-86-3)
- 1-(3-Hydroxy-3-methylbutan-2-yl)-3-(2,2,2-trifluoroethyl)urea (CAS 1280849-90-2)
- 6-Phenyl-5-(piperidin-1-yl)-2,3-dihydropyridazin-3-one (CAS 220967-35-1)
- Valsartan Impurity 76 (CAS CATO-C4X-105776)
- Acetyl decapeptide-3 (CAS 935288-50-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com