Fmoc-Leu-Cl CAS 103321-59-1
| CAS No. | 103321-59-1 |
| Molecular Formula | C21H22ClNO3 |
| Molecular Weight | 371.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Fmoc-Leu-Cl is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Fmoc-Leu-Cl (CAS 103321-59-1), molecular formula C21H22ClNO3 and molecular weight 371.86 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Fmoc-Leu-Cl (C21H22ClNO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Fmoc-Leu-Cl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H22ClNO3 |
| Molecular Weight | 371.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Fmoc Standards
- Fmoc-Ile-Cl (CAS 103321-51-3)
- Fmoc-Cys(Et)-OH (CAS 200354-34-3)
- Fmoc-D-Met-OH (CAS 112883-40-6)
- Fmoc-Met-OH (CAS 71989-28-1)
- 146803-47-6 Fmoc-D-Phe-aldehyde (CAS 146803-47-6)
- Fmoc-PEG3-alcohol (CAS 560088-66-6)
- Fmoc-Leu-OH-<SUP>13</SUP>C<SUB>6</SUB>,<SUP>15</SUP>N (CAS 1163133-36-5)
- Fmoc-Ile-OH-<SUP>13</SUP>C<SUB>6</SUB>,<SUP>15</SUP>N (CAS 1217442-29-9)
Recommended Standards
- Ethyl 2-(4-(4-chlorophenyl)-2,4-dimethyl-3,4-dihydroquinolin-1(2H)-yl)-2-oxoacetate (CAS 1374509-57-5)
- tert-Butyl 4-(7-chloroquinolin-4-yl)-4-cyanopiperidine-1-carboxylate (CAS 1015856-31-1)
- Trazodone EP Impurity C (CAS 157072-19-0)
- Clenbuterol Impurity 2 (CAS 30095-55-7)
- Ethyl 1-ethyl-3-formyl-1H-indole-2-carboxylate (CAS 78358-17-5)
- 4-(Chlorodifluoromethyl)pyrimidine-5-carbonyl chloride (CAS 185393-14-0)
- 3-(4-Chlorobenzoyl)-4-phenyl-1H-pyrrole (CAS 170939-09-0)
- Methyl 5-isopropyl-4,5-dihydroisoxazole-3-carboxylate (CAS 147008-05-7)
- 2-(2-Chloro-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 892845-64-6)
- 1,2,8-Trimethylquinolin-4(1H)-one (CAS 41151-86-4)
- [1-((S)-2-Amino-propionyl)-pyrrolidin-3-ylmethyl]-methyl-carbamic acid tert-butyl ester (CAS 1401664-73-0)
- n-(3-Chloroquinoxalin-2-yl)cyanamide (CAS 499230-61-4)
- 7-(Benzenesulfonyl)-4-chloro-5-iodo-pyrrolo[2,3-d]pyrimidine (CAS 208459-84-1)
- Semaglutide impurity 274 (CAS CATO-C4X-2226274)
Why CATO?
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