2-[1-(4-Chloro-3-fluorobenzyl)-3-oxo-2-piperazinyl]acetic acid CAS 1033600-01-9
| CAS No. | 1033600-01-9 |
| Molecular Formula | C13H14ClFN2O3 |
| Molecular Weight | 300.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-[1-(4-Chloro-3-fluorobenzyl)-3-oxo-2-piperazinyl]acetic acid.
2-[1-(4-Chloro-3-fluorobenzyl)-3-oxo-2-piperazinyl]acetic acid (CAS 1033600-01-9) is a high-purity analytical reference standard with the molecular formula C13H14ClFN2O3 and a molecular weight of 300.71 g/mol.
The molecular framework of 2-[1-(4-Chloro-3-fluorobenzyl)-3-oxo-2-piperazinyl]acetic acid (C13H14ClFN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-[1-(4-Chloro-3-fluorobenzyl)-3-oxo-2-piperazinyl]acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H14ClFN2O3 |
| Molecular Weight | 300.71 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-(1-(2-Chloro-6-fluorobenzyl)-3-oxopiperazin-2-yl)acetic acid (CAS 1033600-27-9)
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Recommended Standards
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- 3-(2-Methoxyethoxy)propanenitrile (CAS 35633-50-2)
- 1-(2-Chlorobenzyl)-5-methyl-1h-1,2,3-triazole-4-carboxylic acid (CAS 1034738-41-4)
- 2-(p-Tolyl)propan-2-yl sulfofluoridate (CAS 62994-87-0)
- (3,4-Dichlorophenyl)(3,5-dimethylphenyl)methanone (CAS 844885-35-4)
- 3-Chloro-2-phenyl-1-tosyl-1H-indole (CAS 88207-51-6)
- Mulberroside A (CAS 102841-42-9)
- 2-Chloro-N-(1-(thiazol-2-yl)ethyl)acetamide (CAS 1225803-85-9)
- Serpent Peptide (CAS 823202-99-9)
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