1,​4-​Bis(isocyanatomethyl​)​cyclohexane CAS 10347-54-3
| CAS No. | 10347-54-3 |
| Molecular Formula | C10H14N2O2 |
| Molecular Weight | 194.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,​4-​Bis(isocyanatomethyl​)​cyclohexane.
CATO supplies 1,​4-​Bis(isocyanatomethyl​)​cyclohexane (CAS 10347-54-3), a certified reference material (molecular formula C10H14N2O2, MW 194.23 g/mol) for analytical method development and quality control.
The molecular framework of 1,​4-​Bis(isocyanatomethyl​)​cyclohexane (C10H14N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1,​4-​Bis(isocyanatomethyl​)​cyclohexane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14N2O2 |
| Molecular Weight | 194.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Nitrogen Atoms | 2 |
Related Bis Standards
- 2-(Isocyanatomethyl)-1,4-dimethoxybenzene (CAS 93489-30-6)
- 4-Isocyanatomethyl-1,2-dimethoxy-benzene (CAS 87665-57-4)
- methyl 4-(isocyanatomethyl)benzoate (CAS 78915-52-3)
- 1-(isocyanatomethyl)-2,4-dimethoxybenzene 93489-13-5 NE28905 (CAS 93489-13-5)
- 1,2-Bis(isocyanatomethyl)benzene (CAS 25854-16-4)
- 1-(Isocyanatomethyl)-4-(trifluoromethyl)benzene (CAS 102422-55-9)
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- 1-(Isocyanatomethyl)-3-(trifluoromethyl)benzene (CAS 52794-59-9)
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