Maprotiline Hydrochloride CAS 10347-81-6
| CAS No. | 10347-81-6 |
| Molecular Formula | C20H23N |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Maprotiline Hydrochloride is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Maprotiline Hydrochloride (CAS 10347-81-6), a certified reference material (molecular formula C20H23NHCl, MW 313.87 g/mol) for analytical method development and quality control.
The molecular framework of Maprotiline Hydrochloride (C20H23NHCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Maprotiline Hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H23N HCl |
| Molecular Weight | 313.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Maprotiline Standards
- Maprotiline (CAS 10262-69-8)
- Maprotiline Hydrochloride EP Impurity B (CAS 1648814-39-4)
- Maprotiline-d5 Hydrochloride (CAS 1794942-12-3)
- Maprotiline EP impurity E (CAS 23941-38-0)
- Maprotiline EP impurity E HCl (CAS 23941-45-9)
- Maprotiline EP impurity B HCl (CAS 2724727-05-1)
- (E)-Maprotiline EP Impurity A (CAS 38849-09-1)
- Maprotiline EP Impurity D HCl (CAS 38849-14-8)
Recommended Standards
- N-(tert-Butyl)-3-piperidinecarboxamidehydrochloride (CAS 937725-07-0)
- 2,6-Dichloro-N-{1-[(2,6-dichlorophenyl)methyl]-2-oxo-1,2-dihydropyridin-3-yl}benzamide (CAS 338784-15-9)
- (2,3-Dimethoxyphenyl)(pyridin-3-yl)methanone (CAS 1187165-41-8)
- Gefitinib EP Impurity B (CAS 1603814-04-5（free base）)
- 2,2,6,6-Tetramethyl-1-(prop-2-yn-1-yl)piperidine (CAS 25665-47-8)
- 3-Fluoro-4-(trifluoromethyl)picolinic acid (CAS 1806385-89-6)
- Methyl (2E)-4-(2,4-Dimethoxyphenyl)-4-oxobut-2-enoate (CAS 87964-01-0)
- (R)-1-(2-(Diphenylphosphanyl)phenyl)-N-methylethan-1-amine (CAS 1332500-23-8)
- N-(1,1-Dioxothian-3-yl)-1-isopropyl-indazol-6-amine (CAS 2371764-07-5)
- Boc-Cholecystokinin Octapeptide (desulfated) (A-1295.0001) (CAS 25687-34-7)
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