4-(3,4-Difluorophenyl)tetrahydro-2H-pyran-4-carbonitrile CAS 1035262-11-3
| CAS No. | 1035262-11-3 |
| Molecular Formula | C12H11F2NO |
| Molecular Weight | 223.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-(3,4-Difluorophenyl)tetrahydro-2H-pyran-4-carbonitrile is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 223.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
4-(3,4-Difluorophenyl)tetrahydro-2H-pyran-4-carbonitrile (CAS 1035262-11-3) is a high-purity analytical reference standard with the molecular formula C12H11F2NO and a molecular weight of 223.22 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(3,4-Difluorophenyl)tetrahydro-2H-pyran-4-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H11F2NO |
| Molecular Weight | 223.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluorophenyl Standards
- 1-[(2,5-Difluorophenyl)methyl]-4-methyl-1H-pyrazol-5-amine (CAS 1152964-00-5)
- 1-(5-(2,6-Difluorophenyl)furan-2-yl)-N-methylmethanamine (CAS 1154331-49-3)
- 1-(5-(2,4-Difluorophenyl)furan-2-yl)-N-methylmethanamine (CAS 1155138-55-8)
- 1-(2,4-Difluorophenyl)-3,5-dimethyl-1h-pyrazol-4-amine (CAS 1156602-37-7)
- (2,4-Difluorophenyl)(1-methyl-1H-imidazol-2-yl)methanamine (CAS 1249710-14-2)
- (3,4-Difluorophenyl)(1-methyl-1H-pyrrol-2-yl)methanol (CAS 1443342-74-2)
- 4-(3,5-Difluorophenyl)tetrahydro-2H-pyran-4-carbonitrile (CAS 179421-07-9)
- (3,4-Difluorophenyl)(1-methyl-1h-imidazol-2-yl)methanamine (CAS 947012-77-3)
Recommended Standards
- n-(2,5-Difluorobenzyl)-1-methyl-1h-pyrazol-4-amine (CAS 1006957-57-8)
- 5-(3-Fluorophenyl)thiazole-4-carboxylic acid (CAS 1047676-31-2)
- 2,4-Difluoro-N-((1-methyl-1h-pyrazol-4-yl)methyl)aniline (CAS 1006466-27-8)
- 2-(2-Fluorophenyl)thiazole-4-carboxylic Acid (CAS 1094373-86-0)
- MDK83190, 98% (CAS 79183-19-0)
- 5-Bromo-6-methylpyrimidin-2(1H)-one hydrobromide (CAS 63331-36-2)
- (3-(Difluoromethoxy)cyclohexyl)methanamine (CAS 1781038-86-5)
- (3-((4-Ethylpiperazin-1-yl)methyl)-4-fluorophenyl)boronic acid (CAS 1704063-94-4)
- n-[4-(2,5-dioxoimidazolidin-4-yl)phenyl]acetamide (CAS 22706-08-7)
- 2-((2-Cyanophenyl)sulfinyl)-N-methylbenzamide (CAS 477710-68-2)
- 2-((Decanoyloxy)methyl)-2-methylpropane-1,3-diyl bis(decanoate) (CAS 67874-05-9)
- 3-Acetoxy-2,6-dimethoxybenzophenone (CAS 890100-40-0)
- 4-(tert-Butyl)phenyl 1,2,3,4-tetrahydroacridine-9-carboxylate (CAS 853317-75-6)
- a2,3-Sialylglycopeptide (CAS 189035-43-6)
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