Levetiracetam Impurity 12 CAS 103765-03-3
| CAS No. | 103765-03-3 |
| Molecular Formula | C4H10N2O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Levetiracetam Impurity 12.
As a process- or degradation-related impurity, Levetiracetam Impurity 12 (CAS 103765-03-3, C4H10N2OHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C4H10N2OHCl, Levetiracetam Impurity 12 contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 138.59 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H10N2O HCl |
| Molecular Weight | 138.59 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Levetiracetam Standards
- Levetiracetam (CAS 102767-28-2)
- Levetiracetam USP Related Compound A (CAS 102767-31-7)
- (S)-Levetiracetam EP Impurity A (CAS 102849-49-0)
- Levetiracetam Impurity- E (IH) (CAS 102916-46-1)
- Levetiracetam EP Impurity D (CAS 103765-01-1)
- Levetiracetam EP Impurity A (CAS 103833-72-3)
- Levetiracetam-d6 (CAS 1133229-29-4)
- Levetiracetam-d6 (CAS 1133229-30-7)
Recommended Standards
- Ornidazole Impurity 43 (CAS CATO-C4X-133143)
- Dexamethasone Impurity 23 (CAS 59860-99-0)
- Methylprednisolone Impurity 81 (CAS 82332-00-1)
- 1H-Indazole-5,7-diamine (CAS 777802-08-1)
- (R)-2-(3,4-difluorophenyl)pyrrolidine (CAS 1241677-04-2)
- Benzo[c][1,2,5]selenadiazol-4-ol (CAS 767-67-9)
- 4-Ethoxy-3-methoxybenzoyl chloride (CAS 3535-36-2)
- (2R,3R,4S,5S)-2-(6-Amino-9H-purin-9-yl)-5-(((3-aminophenyl)thio)methyl)tetrahydrofuran-3,4-diol (CAS 86072-47-1)
- N-(2,4-Dimethoxyphenyl)-2-((3-ethyl-5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 578756-18-0)
- Semaglutide impurity 276 (CAS CATO-C4X-2226276)
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