Dexamethasone Impurity 23 CAS 59860-99-0
| CAS No. | 59860-99-0 |
| Molecular Formula | C22H27FO4 |
| Molecular Weight | 374.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Dexamethasone Impurity 23 (CAS 59860-99-0) is a certified pharmaceutical impurity reference standard with the molecular formula C22H27FO4 and a molecular weight of 374.45 g/mol.
The molecular framework of Dexamethasone Impurity 23 (C22H27FO4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Dexamethasone Impurity 23 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H27FO4 |
| Molecular Weight | 374.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | F-containing |
Related Dexamethasone Standards
- Dexamethasone Oxetanone (CAS 4089-36-5)
- Dexamethasone Impurity 104 (CAS 62800-49-1)
- Dexamethasone Impurity 120 (CAS CATO-C4X-1165120)
- Dexamethasone Impurity 39 (CAS 6762-51-2)
- Dexamethasone Impurity 95 (CAS CATO-C4X-116595)
- Dexamethasone Desfluoro 11-Epimer (CAS 78761-59-8)
- Dexamethasone EP Impurity J (CAS 2036-77-3)
- Dexamethasone EP Impurity D (CAS 24916-90-3)
Recommended Standards
- Donepezil EP impurity E (CAS CATO-C4X-103936)
- Betamethasone Enol Aldehyde Z Isomer (CAS 52647-06-0)
- Tos-PEG2-CH2-Boc (CAS 882518-89-0)
- Betamethasone Enol Aldehyde E Isomer (CAS 52647-07-1)
- Argatroban Impurity 27 (CAS 74892-82-3)
- Stiripentol Impurity 10 (CAS 58344-86-8)
- Atorvastatin Impurity 76 (CAS CATO-C4X-113276)
- 3,5-Dibromoquinoline, 97% (CAS 101861-59-0)
- tert-Butyl 5-benzylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate (CAS 186202-73-3)
- N-(4-(4-chlorophenyl)thiazol-2-yl)-2-(phenylthio)acetamide (CAS 338959-60-7)
- 2-(4-Chloro-2-methylphenoxy)-1-(4-methylpiperazin-1-yl)ethan-1-one (CAS 101991-85-9)
- Topiroxostat Impurity 67 (CAS CATO-C4X-105567)
- 4-(1-{[2-(piperidin-1-yl)pyridin-3-yl]sulfonyl}piperidine-4-carbonyl)morpholine (CAS 1291842-06-2)
- Semaglutide impurity 47 (CAS CATO-C4X-222647)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com