N-Nitroso Fexofenadine EP Impurity E CAS 1038-06-8
| CAS No. | 1038-06-8 |
| Molecular Formula | C18H20N2O2 |
| Molecular Weight | 296.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
N-Nitroso Fexofenadine EP Impurity E (CAS 1038-06-8) is a certified pharmaceutical impurity reference standard with the molecular formula C18H20N2O2 and a molecular weight of 296.36 g/mol.
Based on its molecular formula C18H20N2O2, N-Nitroso Fexofenadine EP Impurity E contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 296.36 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H20N2O2 |
| Molecular Weight | 296.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related N Standards
- N-Nitroso Metoprolol (CAS 138768-62-4)
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Recommended Standards
- Ketoprofen EP Impurity L (Mixture of Enantiomer) (CAS 1797984-80-5)
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- Mianserin Impurity 88 (CAS CATO-C4X-136988)
- Atorvastatin Cyclic Sodium Salt (Isopropyl) Impurity (CAS CATO-CP150633)
- Orlistat impurity 41 (CAS 68659-61-0)
- Ibrutinib Impurity 110 (CAS CATO-C4X-1064110)
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- 1-(1,3,4-Thiadiazol-2-yl)azetidin-3-amine (CAS 1343676-60-7)
- 3-(6-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}pyridin-2-yl)-1-[3-(trifluoromethyl)phenyl]urea (CAS 477864-65-6)
- N-(3-Aminophenyl)-2-phenoxyacetamide (CAS 939230-93-0)
- Methyl 2-cyclopropylthiazole-5-carboxylate (CAS 1286744-61-3)
- 4-Methoxydibenzylamine hydrochloride (CAS 58405-57-5)
- Allo-D-Ile27-Tirzepatide (CAS CATO-CPTD788961)
Why CATO?
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