n-(4-Chlorobenzyl)-1-(thiophen-3-yl)methanamine CAS 1038256-49-3
| CAS No. | 1038256-49-3 |
| Molecular Formula | C12H12ClNS |
| Molecular Weight | 237.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of n-(4-Chlorobenzyl)-1-(thiophen-3-yl)methanamine (C12H12ClNS) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies n-(4-Chlorobenzyl)-1-(thiophen-3-yl)methanamine (CAS 1038256-49-3), a certified reference material (molecular formula C12H12ClNS, MW 237.75 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), n-(4-Chlorobenzyl)-1-(thiophen-3-yl)methanamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H12ClNS |
| Molecular Weight | 237.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related n Standards
- n-(2-Chlorobenzyl)-1-(thiophen-2-yl)methanamine (CAS 66200-70-2)
- n-(4-Chlorobenzyl)-1-(thiophen-2-yl)methanamine (CAS 774190-82-8)
- 3-(4-Chlorobenzyl)-1-methylpiperidin-4-one (CAS 1510489-53-8)
- 6-((4-Chlorobenzyl)oxy)-2-azaspiro[3.3]heptane (CAS 1708160-24-0)
- 1-(1-(4-Chlorobenzyl)-1H-1,2,3-triazol-4-yl)ethan-1-ol (CAS 1443291-22-2)
- 1-(4-Chlorobenzyl)-5-oxopyrrolidine-3-carbaldehyde (CAS 1447962-33-5)
- 1-(3-Chlorobenzyl)piperidine-2,4-dione (CAS 845724-14-3)
- 1-(3-Chlorobenzyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1247438-10-3)
Recommended Standards
- 5-Chloro-2-methyl-N-(thiophen-3-ylmethyl)aniline (CAS 1019631-23-2)
- 2-Chloro-4-methyl-N-(thiophen-3-ylmethyl)aniline (CAS 1039901-30-8)
- 4-Chloro-N-(1-(thiophen-2-yl)ethyl)aniline (CAS 1019619-42-1)
- 2-Chloro-4-methyl-N-(thiophen-2-ylmethyl)aniline (CAS 1040056-01-6)
- 2-Chloro-n-[2-(4-methoxyphenyl)-2-(piperidin-1-yl)ethyl]acetamide hydrochloride (CAS 1049790-47-7)
- Methyl (Z)-1-acetyl-3-(ethoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate (CAS 1175365-43-1)
- [2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]methanamine (CAS 1094329-66-4)
- 3-(4-Nitrophenoxy)pyridine (CAS 28232-53-3)
- 3-(1-Amino-3-methylbutyl)oxetan-3-ol (CAS 2089676-43-5)
- 2-(3-(4-Chloro-1H-indol-1-yl)propanamido)acetic acid (CAS 1219569-89-7)
- 5-Bromo-1-tert-butyl-6-fluorobenzoimidazole (CAS 1187385-67-6)
- 3-Bromo-1h-pyrrolo[2,3-b]pyridine hydrobromide (CAS 1461713-60-9)
- Methyl 5-[(E)-2-[(4-chlorophenyl)amino]ethenyl]-3-(2,6-dichlorophenyl)-1,2-oxazole-4-carboxylate (CAS 338394-32-4)
- 263251-78-1 NMG938VJ6T D-3 Tavilermide [USAN:INN] UNII-NMG938VJ6T MIM-D3 MIM-D 3 D 3 (peptide) Tavilermide (CAS 263251-78-1)
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