Methyl 3-amino-3-(2-chloro-6-fluorophenyl)propanoate CAS 1038338-45-2
| CAS No. | 1038338-45-2 |
| Molecular Formula | C10H11ClFNO2 |
| Molecular Weight | 231.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Methyl 3-amino-3-(2-chloro-6-fluorophenyl)propanoate (C10H11ClFNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 231.65 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Methyl 3-amino-3-(2-chloro-6-fluorophenyl)propanoate (CAS 1038338-45-2), a certified reference material (molecular formula C10H11ClFNO2, MW 231.65 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 3-amino-3-(2-chloro-6-fluorophenyl)propanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11ClFNO2 |
| Molecular Weight | 231.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- Methyl 3-amino-3-(4-chloro-3-fluorophenyl)propanoate (CAS 1250571-73-3)
- 2-Amino-3-(6-chloro-2-fluoro-3-methylphenyl)propanoic acid (CAS 1259982-09-6)
- 2-Amino-3-(2-chloro-6-fluoro-3-methylphenyl)propanoic acid (CAS 1259983-62-4)
- Methyl 2-amino-3-(2-chloro-6-fluorophenyl)propanoate (CAS 1266702-93-5)
- 3-Amino-4-(2-chloro-6-fluorophenyl)butanoic acid (CAS 1267776-94-2)
- 3-Amino-4-(3-chloro-4-fluorophenyl)butanoic acid (CAS 1368458-95-0)
- 3-Amino-4-(5-chloro-2-fluorophenyl)butanoic acid (CAS 1368862-61-6)
- Methyl 3-amino-3-(2-chloro-3-fluorophenyl)propanoate (CAS 1823071-84-6)
Recommended Standards
- Sildenafil Impurity 247 (CAS 360068-47-9)
- 2-(2-Chloro-6-fluorophenyl)-2-(dimethylamino)acetic acid (CAS 1103976-76-6)
- Triazoxide desoxy (CAS 54448-61-2)
- 2-((2-Chloro-6-fluorobenzyl)(methyl)amino)acetic acid (CAS 1156268-41-5)
- Methyl 6-bromo-5-iodo-1H-indole-3-carboxylate (CAS 475641-12-4)
- (4-((4-Chlorophenyl)thio)-3-nitrophenyl)(morpholino)methanone (CAS 303987-89-5)
- rac-methyl (3aR,7aR)-octahydro-1H-isoindole-3a-carboxylate (CAS 1807939-37-2)
- 3-Amino-2-(trifluoromethyl)pyridine-4-acetic acid (CAS 1228898-50-7)
- 3-(Azepan-1-ylsulfonyl)-4-chloro-N-(pyridin-3-yl)benzamide (CAS 377763-51-4)
- Piperidinium iodide (CAS 21701-42-8)
- Methyl benzo[c]isothiazole-4-carboxylate (CAS 56910-98-6)
- 5-(Dimethylamino)-6-methyl-1,2,4-triazin-3-ol (CAS 515116-37-7)
- 7-Fluoro-2-(trifluoromethyl)quinazolin-4-amine (CAS 1494890-30-0)
- Semaglutide impurity 270 (CAS CATO-C4X-2226270)
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