Sildenafil Impurity 247 CAS 360068-47-9
| CAS No. | 360068-47-9 |
| Molecular Formula | C8H10ClN3O3 |
| Molecular Weight | 231.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 231.64 g/mol gives Sildenafil Impurity 247 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Sildenafil Impurity 247 (CAS 360068-47-9) is a certified pharmaceutical impurity reference standard with the molecular formula C8H10ClN3O3 and a molecular weight of 231.64 g/mol.
The molecular framework of Sildenafil Impurity 247 (C8H10ClN3O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Sildenafil Impurity 247 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H10ClN3O3 |
| Molecular Weight | 231.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Sildenafil Standards
- Sildenafil Impurity 34 (CAS CATO-C4X-112834)
- Sildenafil Impurity N6 (CAS 1004455-71-3)
- Sildenafil Impurity N1 (CAS 911715-34-9)
- Sildenafil Impurity SM2 (CAS 202066-14-6)
- Sildenafil Impurity N5 (CAS 60531-34-2)
- Sildenafil Impurity 76 (CAS 97-05-2)
- Sildenafil Impurity 53 (CAS 2021224-02-0)
- Sildenafil RC 41 (CAS 222729-55-7)
Recommended Standards
- Triazoxide desoxy (CAS 54448-61-2)
- Methyl 3-amino-3-(2-chloro-6-fluorophenyl)propanoate (CAS 1038338-45-2)
- Ethyl 2-(5-amino-6-chloropyrimidin-4-yl)hydrazinecarboxylate (CAS 6969-82-0)
- 2-(2-Chloro-6-fluorophenyl)-2-(dimethylamino)acetic acid (CAS 1103976-76-6)
- Ioversol Impurity 14 (CAS CATO-C4X-209114)
- Piroxicam Impurity 23 Disodium Salt (CAS 88741-92-8 (free acid))
- Regorafenib Impurity 55 (CAS 18584-93-5)
- 4-Methyl-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidine-1-carboxamide (CAS 874297-89-9)
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-pyridinol (CAS 1244772-69-7)
- 4-Bromo-1,2-dimethyl-5-nitro-1H-imidazole (CAS 21431-58-3)
- 1-Isopropyl-1h-pyrazole-4-thiol (CAS 1361004-09-2)
- 2-({2-[2-(4-Methoxyphenoxy)acetyl]hydrazino}carbonyl)cyclohexanecarboxylic acid (CAS 670247-34-4)
- 1-(6-Methoxypyridin-3-yl)-N-methylmethanamine (CAS 179873-20-2)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com