4-Amino-1-((4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one CAS 103882-84-4
| CAS No. | 103882-84-4 |
| Molecular Formula | C9H11F2N3O4 |
| Molecular Weight | 263.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-Amino-1-((4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one (CAS 103882-84-4), a certified reference material (molecular formula C9H11F2N3O4, MW 263.20 g/mol) for analytical method development and quality control.
Based on its molecular formula C9H11F2N3O4, 4-Amino-1-((4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 263.20 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 4-Amino-1-((4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H11F2N3O4 |
| Molecular Weight | 263.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 5-Amino-1-(3,4-difluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one (CAS 1416348-31-6)
- 4-Amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one (CAS 701937-51-1)
- (S)-2-Amino-4-(2-(trifluoromethoxy)phenyl)butanoic acid (CAS 1260590-74-6)
- (R)-2-Amino-4-(3-(trifluoromethoxy)phenyl)butanoic acid (CAS 1260607-86-0)
- 3-Amino-2-(3-(trifluoromethoxy)benzyl)propanoic acid (CAS 1260607-90-6)
- (S)-2-Amino-4-(4-(trifluoromethoxy)phenyl)butanoic acid (CAS 1260610-29-4)
- (R)-3-amino-2-(2-(trifluoromethoxy)benzyl)propanoic acid (CAS 1260611-02-6)
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Recommended Standards
- 1-[(1,3-Benzodioxol-5-ylcarbonyl)oxy]pyrrolidine-2,5-dione (CAS 102132-54-7)
- Gemcitabine Impurity N1 (CAS 103882-85-5)
- 1-(2,4-Difluorophenyl)-4-(1H-1,2,4-triazol-1-yl)-1H-pyrazol-5-ol (CAS 1007014-95-0)
- (2,6-Difluoro-3-nitrophenyl)(phenyl)methanone (CAS 1145881-51-1)
- Tetrapropylammonium Hydroxide (10% in Water) (CAS 4499-86-9)
- 3-Chloro-4-fluoropyridin-2-amine (CAS 1393570-09-6)
- 4-(2-Aminoethyl)benzamide (CAS 90513-12-5)
- 5-Amino-2-(((5-methylthiophen-2-yl)methyl)amino)pyrimidin-4(1H)-one (CAS 77961-58-1)
- 3-Amino-1-(3,5,6,7-tetrahydrospiro[imidazo[4,5-c]pyridine-4,4'-piperidin]-1'-yl)propan-1-one (CAS 1092292-66-4)
- di-tert-Butyl 2-methyl-2-(5-(tosyloxy)pentyl)malonate (CAS 1236354-13-4)
- 2,2,2-Trifluoro-1-(3-fluoro-4-methoxyphenyl)ethan-1-amine hcl (CAS 1803606-55-4)
- N-(azetidin-3-yl)-2-methoxyacetamide hydrochloride (CAS 1803592-26-8)
- Salbutamol Impurity 77 (CAS 39235-57-9)
- Lixisenatide (CAS 320367-13-3（free base）)
Why CATO?
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