N-(3-chlorophenyl)-2-((3-methyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide CAS 1040682-53-8
| CAS No. | 1040682-53-8 |
| Molecular Formula | C21H16ClN3O2S2 |
| Molecular Weight | 441.95 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 441.95 g/mol gives N-(3-chlorophenyl)-2-((3-methyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-(3-chlorophenyl)-2-((3-methyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1040682-53-8) is a high-purity analytical reference standard with the molecular formula C21H16ClN3O2S2 and a molecular weight of 441.95 g/mol.
The molecular framework of N-(3-chlorophenyl)-2-((3-methyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (C21H16ClN3O2S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H16ClN3O2S2 |
| Molecular Weight | 441.95 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related N Standards
- N-(4-chlorophenyl)-2-((3-methyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1040633-95-1)
- N-(2-chlorophenyl)-2-((3-methyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1040682-45-8)
- (E)-{[4-(4-chlorophenyl)-7-thia-2,5-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),3,5-trien-3-yl]methylidene}amino thiophene-2-carboxylate (CAS 478041-87-1)
- 2-(4-(1-(4-Chlorophenyl)-4-(piperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)piperazin-1-yl)ethanol (CAS 1207046-09-0)
- 1-(4-Chlorophenyl)-N-[(3,4-dimethoxyphenyl)methyl]-3-methyl-1H-thieno[2,3-c]pyrazole-5-carboxamide (CAS 380461-32-5)
- 2-(4-Chlorophenyl)-5-(3-ethoxy-4-propoxybenzylidene)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 617694-31-2)
- 2-[4-({4-[(4-chlorophenyl)sulfanyl]-3-nitrophenyl}methyl)piperazin-1-yl]pyrimidine (CAS 477869-40-2)
- 4-[(4-Chlorophenyl)sulfanyl]-6-[4-(2-ethoxyphenyl)piperazin-1-yl]pyrimidin-2-amine (CAS 339017-66-2)
Recommended Standards
- (S)-1-(2-(3-(3-(2-(7-Chloroquinolin-2-yl)vinyl)phenyl)-3-hydroxypropyl)phenyl)ethan-1-one (CAS 144551-23-5)
- N-Nitroso Ziprasidone (CAS CATO-C4X-124053)
- (R)-tert-Butyl 1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropylcarbamate (CAS 587881-33-2)
- 7-Chloro-5-(3-methylpiperidin-1-yl)-3-(phenylsulfonyl)-[1,2,3]triazolo[1,5-a]quinazoline (CAS 904580-16-1)
- 1-(2,4-dihydroxy-5-methylphenyl)ethanone (CAS 93578-16-6)
- 1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid (CAS 100957-85-5)
- tert-Butyl 2-(((2-aminoethyl)thio)methyl)piperidine-1-carboxylate (CAS 1353973-93-9)
- 2-(2-Methoxyethyl)-1h-benzo[d]imidazole-5-carboxylic acid (CAS 1082893-13-7)
- 2-(3-Bromo-2-oxoindolin-3-yl)acetic acid (CAS 64230-47-3)
- (3,4-Bis(difluoromethoxy)phenyl)methanol (CAS 153587-06-5)
- Eltrombopag Impurity 118 (CAS CATO-C4X-1198118)
- (Z)-retro-α-Ionol (CAS 55093-47-5)
- Ethyl 8-bromo-6-methylimidazo[1,2-a]pyridine-2-carboxylate (CAS 847446-55-3)
- Liraglutide Impurity 14 TFA Salt (CAS CATO-C4X-199214)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com