4-[(4-Chlorophenyl)sulfanyl]-6-[4-(2-ethoxyphenyl)piperazin-1-yl]pyrimidin-2-amine CAS 339017-66-2
| CAS No. | 339017-66-2 |
| Molecular Formula | C22H24ClN5OS |
| Molecular Weight | 441.98 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-[(4-Chlorophenyl)sulfanyl]-6-[4-(2-ethoxyphenyl)piperazin-1-yl]pyrimidin-2-amine is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-[(4-Chlorophenyl)sulfanyl]-6-[4-(2-ethoxyphenyl)piperazin-1-yl]pyrimidin-2-amine (CAS 339017-66-2), a certified reference material (molecular formula C22H24ClN5OS, MW 441.98 g/mol) for analytical method development and quality control.
4-[(4-Chlorophenyl)sulfanyl]-6-[4-(2-ethoxyphenyl)piperazin-1-yl]pyrimidin-2-amine (C22H24ClN5OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H24ClN5OS |
| Molecular Weight | 441.98 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 2-(4-(1-(4-Chlorophenyl)-4-(piperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)piperazin-1-yl)ethanol (CAS 1207046-09-0)
- N-(4-chlorophenyl)-2-((3-methyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1040633-95-1)
- N-(2-chlorophenyl)-2-((3-methyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1040682-45-8)
- N-(3-chlorophenyl)-2-((3-methyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1040682-53-8)
- (E)-{[4-(4-chlorophenyl)-7-thia-2,5-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),3,5-trien-3-yl]methylidene}amino thiophene-2-carboxylate (CAS 478041-87-1)
- 1-(4-Chlorophenyl)-N-[(3,4-dimethoxyphenyl)methyl]-3-methyl-1H-thieno[2,3-c]pyrazole-5-carboxamide (CAS 380461-32-5)
- 2-(4-Chlorophenyl)-5-(3-ethoxy-4-propoxybenzylidene)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 617694-31-2)
- 2-[4-({4-[(4-chlorophenyl)sulfanyl]-3-nitrophenyl}methyl)piperazin-1-yl]pyrimidine (CAS 477869-40-2)
Recommended Standards
- 1H,1H,7H-Dodecafluoroheptyl iodide (CAS 376-32-9)
- 3-chloro-2-hydroxypropyl dihydrogen phosphate (CAS 56729-01-2)
- Indapamide Impurity 49 (CAS CATO-C4X-140049)
- Bis(2,4-dichloro-5-nitrophenyl) carbonate (CAS 39489-75-3)
- (2,6-Dimethylphenyl)methanesulfonyl chloride (CAS 540524-67-2)
- (4,5,6,7-Tetrahydropyrazolo[1,5-a]pyridin-3-yl)boronic acid (CAS 1346526-59-7)
- 5-Nitroindole (CAS 6146-52-7)
- 2',6'-Dimethoxy-[1,1'-biphenyl]-4-carbaldehyde (CAS 791839-59-3)
- 4-Allyl-5-(benzo[d][1,3]dioxol-5-yl)-4H-1,2,4-triazole-3-thiol (CAS 77803-46-4)
- 6-(4-Methoxybenzyl)-3-methyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one (CAS 86927-78-8)
- 4-Chloro-N-(3,5-dichlorophenyl)-5H-1,2,3-dithiazol-5-imine (CAS 65374-57-4)
- (Z)-[2-{(3R,4R,5R)-3,5-Bis(tert-butyldimethylsilanyloxy)-2-methylene-4-(3-(tert-butyldiphenylsilanyloxy)propoxy)cyclohexylidene}ethyl]diphenylphosphine oxide (CAS 1254276-84-0)
- Phloroglucinol impurity 64 (CAS CATO-C4X-221764)
- C-telopeptide (CAS 162929-64-8)
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