Ethyl 4-chloro-2,6-bis(trifluoromethyl)nicotinate CAS 104232-04-4
| CAS No. | 104232-04-4 |
| Molecular Formula | C10H6ClF6NO2 |
| Molecular Weight | 321.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 4-chloro-2,6-bis(trifluoromethyl)nicotinate.
Ethyl 4-chloro-2,6-bis(trifluoromethyl)nicotinate (CAS 104232-04-4) is a high-purity analytical reference standard with the molecular formula C10H6ClF6NO2 and a molecular weight of 321.60 g/mol.
Ethyl 4-chloro-2,6-bis(trifluoromethyl)nicotinate (C10H6ClF6NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 4-chloro-2,6-bis(trifluoromethyl)nicotinate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H6ClF6NO2 |
| Molecular Weight | 321.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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- 4-((Methylsulfinyl)methyl)benzonitrile (CAS 163816-22-6)
- tert-butyl (2S)-2-(2-chloroacetyl)pyrrolidine-1-carboxylate (CAS 102284-41-3)
- Semaglutide impurity 251 (CAS CATO-C4X-2226251)
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