Granisetron Impurity C57 CAS 1044956-47-9
| CAS No. | 1044956-47-9 |
| Molecular Formula | C18H24N4O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Granisetron Impurity C57 (C18H24N4OHCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Granisetron Impurity C57 (CAS 1044956-47-9) is a certified pharmaceutical impurity reference standard with the molecular formula C18H24N4OHCl and a molecular weight of 348.88 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Granisetron Impurity C57 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H24N4O HCl |
| Molecular Weight | 348.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Granisetron Standards
- Granisetron Impurity 27 (CAS 10604-20-3)
- Granisetron Impurity 12 (CAS 106649-02-9)
- Granisetron EP Impurity B (CAS 107007-95-4)
- Granisetron Hydrochloride (CAS 107007-99-8)
- Granisetron (CAS 109889-09-0)
- Granisetron-d3 (CAS 1224925-76-1)
- Granisetron Impurity 11(Mixture of Z and E Isomers) (CAS 123704-98-3)
- Granisetron Impurity 10 (CAS 123704-99-4)
Recommended Standards
- Vigabatrin Impurity 9 (CAS 71107-20-5)
- Tofacitinib Impurity 237 (CAS CATO-C4X-1079237)
- Carbidopa EP Impurity A Sesquihydrate (CAS 41372-08-1)
- 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoxazole (CAS 1346808-44-3)
- {2-[(6-bromonaphthalen-2-yl)oxy]ethyl}(methyl)amine hydrochloride (CAS 1211328-07-2)
- N-methyl-N-(tetrahydrothiophen-3-yl)azetidine-3-carboxamide (CAS 1479417-31-6)
- tert-Butyl 6-(hydroxymethyl)-5,6,7,9-tetrahydroimidazo[1,2-a][1,4]diazepine-8-carboxylate (CAS 1251017-49-8)
- 4-Methoxy-1-nitro-2-(trifluoromethoxy)benzene (CAS 1260770-16-8)
- 2-(3,4-Dichloro-benzyloxymethyl)-6-methoxy-benzoic acid methyl ester (CAS 1171923-68-4)
- (Tyr9)-Cholecystokinin Octapeptide (sulfated) (H-9770.0005) (CAS 96607-61-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com