4-(Pyridin-2-yl)pyrrolidine-3-carboxylic acid CAS 1048333-66-9
| CAS No. | 1048333-66-9 |
| Molecular Formula | C10H12N2O2 |
| Molecular Weight | 192.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(Pyridin-2-yl)pyrrolidine-3-carboxylic acid (C10H12N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4-(Pyridin-2-yl)pyrrolidine-3-carboxylic acid (CAS 1048333-66-9), molecular formula C10H12N2O2 and molecular weight 192.21 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(Pyridin-2-yl)pyrrolidine-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12N2O2 |
| Molecular Weight | 192.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
Related Pyridin Standards
- 4-(Pyridin-4-yl)pyrrolidine-3-carboxylic acid (CAS 1048330-65-9)
- 1-(Pyridin-3-yl)pyrrolidine-3-carboxylic acid (CAS 1086374-86-8)
- (2S)-1-(Pyridin-2-yl)pyrrolidine-2-carboxylic acid (CAS 1104077-35-1)
- 1-(Pyridin-2-ylmethyl)azetidine-3-carboxylic acid (CAS 1127402-59-8)
- 1-(Pyridin-4-yl)pyrrolidine-3-carboxylic acid (CAS 80028-26-8)
- N-(Pyridin-2-yl)tetrahydrofuran-2-carboxamide (CAS 600159-64-6)
- [2-(pyridin-4-yl)-1,3-thiazol-4-yl]methanol (CAS 1176618-90-8)
- 5-Methyl-2-(pyridin-2-yl)thiazol-4-ol (CAS 131786-47-5)
Recommended Standards
- (3S,4S)-4-(pyridin-2-yl)pyrrolidine-3-carboxylic acid (CAS 1049980-18-8)
- Ethyl (E)-3-(2-aminopyridin-3-yl)acrylate (CAS 104830-07-1)
- 7-Methoxy-2,3-dihydro-1H-indene-1-carboxylic acid (CAS 105211-00-5)
- Ethyl 3-(4-Amino-3-pyridyl)acrylate (CAS 104830-01-5)
- 2-(4-(Difluoromethyl)-6-hydroxy-5-methoxypyridin-2-yl)acetonitrile (CAS 1805535-42-5)
- 3-(Benzyloxy)-N-methoxy-N-methylbenzamide (CAS 615558-47-9)
- Z-D-Trp-OH (CAS 2279-15-4)
- 6-Bromo-2-(chloromethyl)benzimidazole Hydrochloride (CAS 89218-87-1)
- 3-(Chloromethyl)piperidine (CAS 220510-75-8)
- 4-tert-Butyl-4'-iodobiphenyl (CAS 320339-03-5)
- Cholecalciferol impurity 24 (CAS 300692-92-6)
- 5-Bromo-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-6-carbonitrile (CAS 1190322-12-3)
- (1R,2R)-N1,N1-diethylcyclohexane-1,2-diamine (CAS 107298-93-1)
- Xenopsin-Related Peptide 2 (XP-2) (H-9340.0005) (CAS 117442-29-2)
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