1-(Pyridin-4-yl)pyrrolidine-3-carboxylic acid CAS 80028-26-8
| CAS No. | 80028-26-8 |
| Molecular Formula | C10H12N2O2 |
| Molecular Weight | 192.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(Pyridin-4-yl)pyrrolidine-3-carboxylic acid (C10H12N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 1-(Pyridin-4-yl)pyrrolidine-3-carboxylic acid (CAS 80028-26-8), a certified reference material (molecular formula C10H12N2O2, MW 192.21 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(Pyridin-4-yl)pyrrolidine-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12N2O2 |
| Molecular Weight | 192.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 2 |
Related Pyridin Standards
- 4-(Pyridin-4-yl)pyrrolidine-3-carboxylic acid (CAS 1048330-65-9)
- 4-(Pyridin-2-yl)pyrrolidine-3-carboxylic acid (CAS 1048333-66-9)
- 1-(Pyridin-3-yl)pyrrolidine-3-carboxylic acid (CAS 1086374-86-8)
- (2S)-1-(Pyridin-2-yl)pyrrolidine-2-carboxylic acid (CAS 1104077-35-1)
- 1-(Pyridin-2-ylmethyl)azetidine-3-carboxylic acid (CAS 1127402-59-8)
- N-(Pyridin-2-yl)tetrahydrofuran-2-carboxamide (CAS 600159-64-6)
- [2-(pyridin-4-yl)-1,3-thiazol-4-yl]methanol (CAS 1176618-90-8)
- 5-Methyl-2-(pyridin-2-yl)thiazol-4-ol (CAS 131786-47-5)
Recommended Standards
- 1-(Furan-2-yl)bicyclo[2.1.1]Hexane-5-carboxylic acid (CAS 2167496-52-6)
- 1,1'-(3,6-Dimethylpyrazine-2,5-diyl)diethanone (CAS 62025-68-7)
- 1-(benzyloxy)cyclopropane-1-carboxylic acid (CAS 865798-44-3)
- 1,1'-(5-Methoxy-1,3-phenylene)diethanone (CAS 35227-79-3)
- 5-Bromo-2-{[(4-Fluorobenzoyl)Carbamothioyl]Amino}Benzoic Acid (CAS 586391-99-3)
- (R)-2-((1-Acetylpiperidin-3-yl)(methyl)amino)acetic acid (CAS 1354002-88-2)
- 3-(2-Methylphenyl)oxirane-2-carboxylic acid (CAS 1287218-33-0)
- 5-(Dimethoxymethyl)-5-pentylimidazolidine-2,4-dione (CAS 5460-99-1)
- 2-Bromo-4-cyclopropoxy-3-(methylthio)pyridine (CAS 1243397-16-1)
- 1-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-4,6-dichloroimidazo[4,5-c]pyridine (CAS 63423-94-9)
- n-(4,5,6,7-Tetrahydrothiazolo[5,4-c]pyridin-2-yl)cyclopropanecarboxamide hydrochloride (CAS 1351598-79-2)
- N-(Tetrahydro-2H-pyran-4-ylcarbonyl)alanine (CAS 1309036-06-3)
- 2-(Cyclobutoxymethyl)pentane-1-sulfonyl chloride (CAS 1479816-14-2)
- Palmitoyl Tetrapeptide-7 (CAS 221227-05-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com