1-[(3,4-Dichlorophenyl)methyl]-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea CAS 1048916-20-6
| CAS No. | 1048916-20-6 |
| Molecular Formula | C24H20Cl2N4O2 |
| Molecular Weight | 467.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1-[(3,4-Dichlorophenyl)methyl]-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea (CAS 1048916-20-6), a certified reference material (molecular formula C24H20Cl2N4O2, MW 467.35 g/mol) for analytical method development and quality control.
Structurally, 1-[(3,4-Dichlorophenyl)methyl]-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea (C24H20Cl2N4O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 467.35 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H20Cl2N4O2 |
| Molecular Weight | 467.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Dichlorophenyl Standards
- 1-[(2,4-Dichlorophenyl)methyl]-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea (CAS 1796893-26-9)
- N-(2,4-Dichlorophenyl)-3-(dimethylamino)-4-(4-phenoxyphenyl)-1H-pyrazole-1-carboxamide (CAS 321553-16-6)
- N-(3,5-dichlorophenyl)-1-((3-(trifluoromethyl)phenyl)sulfonyl)pyrrolidine-2-carboxamide (CAS 317822-01-8)
- 4-[(3,4-Dichlorophenyl)methoxy]-N'-[(1E)-(3,4-dichlorophenyl)methylidene]benzohydrazide (CAS 320423-45-8)
- 2-(2,4-Dichlorophenyl)-N-(4-methoxy-2-nitrophenyl)quinoline-4-carboxamide (CAS 337502-45-1)
- 2-(2,4-Dichlorophenyl)-1-methyl-3,4-bis(4-methylbenzoyl)pyrrolidine (CAS 1005270-68-7)
- 4-(2,6-Dichlorophenyl)-9-hydroxy-6-(3-(methylamino)propyl)pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione (CAS 622856-21-7)
- N-[4-({1-[(3,4-dichlorophenyl)methyl]-6-oxo-1,6-dihydropyridin-3-yl}sulfamoyl)phenyl]acetamide (CAS 339009-16-4)
Recommended Standards
- Fluoxetine impurity 49 (CAS 1456616-19-5)
- Ethyl 6-bromo-2-(((((4-fluorophenyl)thio)methyl)amino)methyl)-5-hydroxy-1-methyl-1H-indole-3-carboxylate (CAS 1704066-65-8)
- tert-butyl N-tert-butoxycarbonyl-N-(3-iodoimidazo[1,2-a]pyridin-6-yl)carbamate (CAS 2698371-92-3)
- N-(5-((2-((4-Bromophenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)-4-fluorobenzamide (CAS 393566-95-5)
- Propyl pyrrolidine-1-carboxylate (CAS 500299-62-7)
- 2-(1-Bromovinyl)pyridine (CAS 67200-49-1)
- 2,3,5-Trichloropyridin-4-ol (CAS 1970-40-7)
- 4-PHENYL-3-(PIPERIDIN-4-YL)OXAZOLIDIN-2-ONE HCL (CAS 1965309-16-3)
- (1R)-3-ethynylcyclopent-2-en-1-amine;hydrochloride (CAS 1868051-18-6)
- 2-Methyl-5-(trifluoromethoxy)benzamide (CAS 1261828-46-9)
- 5-Thiomorpholinothiophene-2-carbaldehyde (CAS 937604-40-5)
- 6-Chloro-2-fluoro-3-methoxyaniline (CAS 1017777-77-3)
- 4,6-Dichloro-5-methylpyrimidine (CAS 4316-97-6)
- D-[Phe]6-Semaglutide (CAS CATO-CPTD788633)
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