Fluoxetine impurity 49 CAS 1456616-19-5
| CAS No. | 1456616-19-5 |
| Molecular Formula | C21H26INO3 |
| Molecular Weight | 467.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 467.34 g/mol gives Fluoxetine impurity 49 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Fluoxetine impurity 49 (CAS 1456616-19-5, C21H26INO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Fluoxetine impurity 49 (C21H26INO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Fluoxetine impurity 49 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H26INO3 |
| Molecular Weight | 467.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Fluoxetine Standards
- Fluoxetine Impurity 34(Mixture of Isomers) (CAS CATO-C4X-135234)
- Fluoxetine Impurity 14 (CAS CATO-C4X-135214)
- Fluoxetine Impurity 19 (CAS 1026723-45-4)
- Fluoxetine Impurity 15 (CAS CATO-C4X-135215)
- Fluoxetine Impurity 21 (CAS CATO-C4X-135221)
- Fluoxetine Impurity 17 (CAS CATO-C4X-135217)
- Fluoxetine Impurity 50 (CAS CATO-C4X-135250)
- Fluoxetine Impurity 41 (CAS CATO-C4X-135241)
Recommended Standards
- tert-butyl N-tert-butoxycarbonyl-N-(3-iodoimidazo[1,2-a]pyridin-6-yl)carbamate (CAS 2698371-92-3)
- 1-[(3,4-Dichlorophenyl)methyl]-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea (CAS 1048916-20-6)
- N-(5-((2-((4-Bromophenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)-4-fluorobenzamide (CAS 393566-95-5)
- Ethyl 6-bromo-2-(((((4-fluorophenyl)thio)methyl)amino)methyl)-5-hydroxy-1-methyl-1H-indole-3-carboxylate (CAS 1704066-65-8)
- Tolvaptan Impurity 106 (CAS 792931-77-2)
- Indacaterol Impurity 1 (CAS 2338-18-3)
- Ceftiofur Impurity 3 (CAS 120882-20-4)
- 6,7-Dichloro-2-methylquinolin-8-amine (CAS 61854-67-9)
- L-759,656 (CAS 174627-56-6)
- 5-(4-Chlorophenyl)isoxazole-3-carbonitrile (CAS 1173252-25-9)
- 4-Fluoro-N-methyl-N-propylbenzamide (CAS 1184123-88-3)
- 6,7-Dihydro-5H-cyclopenta[b]pyridin-5-one hydrochloride (CAS 1220039-95-1)
- N,N-Dimethyl-2-((pyridin-2-ylmethyl)amino)ethanesulfonamide dihydrochloride (CAS 1203184-98-8)
- Peptide YY (3-36) (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 126339-09-1)
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