Gatifloxacin Impurity 18 CAS 1048972-69-5
| CAS No. | 1048972-69-5 |
| Molecular Formula | C19H22FN3O4 |
| Molecular Weight | 375.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Gatifloxacin Impurity 18.
Gatifloxacin Impurity 18 (CAS 1048972-69-5) is a certified pharmaceutical impurity reference standard with the molecular formula C19H22FN3O4 and a molecular weight of 375.39 g/mol.
The molecular framework of Gatifloxacin Impurity 18 (C19H22FN3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Gatifloxacin Impurity 18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H22FN3O4 |
| Molecular Weight | 375.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Gatifloxacin Standards
- Gatifloxacin Impurity 23 (CAS 112811-58-2)
- Gatifloxacin USP RC E (CAS 1029364-65-5)
- Gatifloxacin (CAS 112811-59-3)
- Iso Gatifloxacin-d3DISCONTINUED (CAS 1794754-08-7)
- Gatifloxacin-d4 (CAS 1190043-25-4)
- Gatifloxacin Impurity 4 (CAS 103460-89-5)
- Gatifloxacin Impurity 27 (CAS CATO-C4X-125327)
- Gatifloxacin Related Compound D(3-Desmethyl Gatifloxacin) (CAS 112811-57-1)
Recommended Standards
- Sitagliptin Impurity 102 (CAS CATO-C4X-1144102)
- N-(2,4-difluorophenyl)-3-((4-methoxybenzyl)oxy)thiophene-2-carboxamide (CAS 339098-34-9)
- Methyl 5-bromo-2-chloro-3-iodobenzoate (CAS 933672-38-9)
- Retigabine Impurity 2 (CAS CATO-C4X-13142)
- Suvorexant Impurity 14 (CAS 2941-79-9)
- Levodopa EP Impurity C (CAS 7636-26-2)
- Allisartan Isoproxil Impurity 12 (CAS CATO-C4X-321712)
- (3-Bromo-1-cyclopropyl-1H-1,2,4-triazol-5-yl)methanol (CAS 2639836-80-7)
- (3R,4R)-4-(Hydroxymethyl)piperidin-3-ol (CAS 1416553-81-5)
- N-(5-bromo-1,6-naphthyridin-2-yl)acetamide (CAS 1330752-53-8)
- (1R,4aS,7aS)-Methyl 1-ethoxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate (CAS 1629668-62-7)
- 2-Methyl-5-(thiomorpholine-4-carbonyl)phenol (CAS 1042634-32-1)
- 1-(1-Benzyl-2,5-dimethyl-1H-pyrrol-3-yl)-2-((1-methyl-1H-tetrazol-5-yl)thio)ethan-1-one (CAS 796093-87-3)
- Neuropeptide K (human, porcine, rat) trifluoroacetate salt (CAS 96827-05-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com