Moxifloxacin Impurity 153 CAS 1048972-52-6
| CAS No. | 1048972-52-6 |
| Molecular Formula | C14H12FNO5 |
| Molecular Weight | 293.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Moxifloxacin Impurity 153 (CAS 1048972-52-6) is a certified pharmaceutical impurity reference standard with the molecular formula C14H12FNO5 and a molecular weight of 293.25 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Moxifloxacin Impurity 153 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 293.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H12FNO5 |
| Molecular Weight | 293.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Moxifloxacin Standards
- Moxifloxacin Impurity 28 (CAS 172426-88-9)
- Moxifloxacin Impurity 109 (CAS 1641561-55-8)
- Moxifloxacin Impurity 12 (CAS 112811-72-0)
- Moxifloxacin impurity 175 (CAS 104599-90-8)
- Moxifloxacin Impurity 71 (CAS 56113-42-9)
- Moxifloxacin Impurity 27 (CAS 94695-52-0)
- Moxifloxacin Impurity 170 (CAS CATO-C4X-1074170)
- Moxifloxacin Impurity 23 (CAS 154093-72-8)
Recommended Standards
- n-Benzyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6(5h)-imine (CAS 338962-59-7)
- rac Tenofovir-d6 (CAS 1020719-94-1)
- Ethyl 2-(((1-(4-fluorophenyl)-1H-tetrazol-5-yl)methyl)amino)-2-oxoacetate (CAS 921060-06-2)
- Ketorolac Impurity 21 (CAS CATO-C4X-166921)
- Brinzolamide Impurity 2 (CAS CATO-C4X-19402)
- Sitafloxacin Impurity N14 (CAS 127199-27-3)
- Tenofovir alafenamide impurity 87 (CAS CATO-C4X-179787)
- 2-(4-Methylpiperazino)-5-trifluoromethylpyridine (CAS 192564-53-7)
- n,n-Diethyl-2-(8-methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetamide (CAS 849045-03-0)
- Sodium 7-chloro-4-hydroxyquinoline-2-carboxylate (CAS 1263094-00-3)
- 2-Methyl-5-(3-methyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)aniline (CAS 708291-98-9)
- 3-(4-Methoxyphenyl)-3-(2,2,2-trifluoroacetamido)propanamide (CAS 444151-78-4)
- 6-Chloro-chroman-2-one (CAS 4377-63-3)
- Calcium-Like Peptide 3 (CAS 261969-05-5)
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