4-(Chloromethyl)-2-(thiophen-3-yl)thiazole hydrochloride CAS 1049745-43-8
| CAS No. | 1049745-43-8 |
| Molecular Formula | C8H6ClNS2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-(Chloromethyl)-2-(thiophen-3-yl)thiazole hydrochloride (CAS 1049745-43-8), a certified reference material (molecular formula C8H6ClNS2HCl, MW 252.17 g/mol) for analytical method development and quality control.
Based on its molecular formula C8H6ClNS2HCl, 4-(Chloromethyl)-2-(thiophen-3-yl)thiazole hydrochloride contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 252.17 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 4-(Chloromethyl)-2-(thiophen-3-yl)thiazole hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6ClNS2 HCl |
| Molecular Weight | 252.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Chloromethyl Standards
- 7-(Chloromethyl)-3-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-81-4)
- 7-(Chloromethyl)-2,3-dimethyl-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-82-5)
- 7-(Chloromethyl)-3-(4-chlorophenyl)-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-85-8)
- chloromethyl 2-ethoxy-2-methylpropanoate (CAS 1000296-74-1)
- 5-(chloromethyl)-N-(4-methylbenzyl)-1,3,4-thiadiazole-2-carboxamide (CAS 1000932-24-0)
- 5-(Chloromethyl)-7-ethoxy-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 1000932-47-7)
- 5-(chloromethyl)-N-(4-fluorobenzyl)-1,3,4-thiadiazole-2-carboxamide (CAS 1000932-60-4)
- 2-(Chloromethyl)-5,6-diphenylfuro[2,3-d]pyrimidin-4-amine (CAS 1000933-67-4)
Recommended Standards
- 2-({[(tert-butoxy)carbonyl]amino}oxy)-2-methylpropanoic acid (CAS 1785364-49-9)
- 4-Bromo-2-fluoro-6-methoxybenzaldehyde (CAS 856767-09-4)
- 5,6,7,8-Tetrahydro-2-methyl[1]benzothieno[2,3-d]pyrimidine-4(3H)-thione (CAS 23922-04-5)
- 1-(3,5-Difluorobenzyl)-1H-imidazole (CAS 170166-01-5)
- Ethyl 5-hydroxybenzofuran-3-carboxylate (CAS 114195-14-1)
- 4-(4-Chlorophenyl)-2-((4-chlorophenyl)thio)-4-oxobutanoic acid (CAS 301193-87-3)
- Troxipide Impurity 3 (CAS 138022-02-3)
- 2,3,5,6-Tetrafluorotyrosine (CAS 157807-84-6)
- Cysteamine (CAS 60-23-1)
- Semaglutide impurity 202 (CAS CATO-C4X-2226202)
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