1-(3,5-Difluorobenzyl)-1H-imidazole CAS 170166-01-5
| CAS No. | 170166-01-5 |
| Molecular Formula | C10H8F2N2 |
| Molecular Weight | 194.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 194.18 g/mol gives 1-(3,5-Difluorobenzyl)-1H-imidazole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(3,5-Difluorobenzyl)-1H-imidazole (CAS 170166-01-5) is a high-purity analytical reference standard with the molecular formula C10H8F2N2 and a molecular weight of 194.18 g/mol.
The molecular framework of 1-(3,5-Difluorobenzyl)-1H-imidazole (C10H8F2N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(3,5-Difluorobenzyl)-1H-imidazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8F2N2 |
| Molecular Weight | 194.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluorobenzyl Standards
- 1-(2,4-Difluorobenzyl)-1H-imidazole (CAS 1340454-54-7)
- 1-(2,5-Difluorobenzyl)-1H-imidazole (CAS 1342052-35-0)
- 1-(2,6-Difluorobenzyl)-1H-imidazole (CAS 1378819-89-6)
- 1-(3,4-Difluorobenzyl)-1H-imidazole (CAS 906478-71-5)
- 1-(3,4-Difluorobenzyl)-1H-pyrrole (CAS 1247669-63-1)
- N-(2,5-difluorobenzyl)acrylamide (CAS 1342290-81-6)
- 3-(2,5-Difluorobenzyl)pyrrolidine (CAS 1100640-03-6)
- (S)-2-(3,4-difluorobenzyl)pyrrolidine (CAS 1232829-80-9)
Recommended Standards
- 3-Acetoxy-2-methylbenzoic acid (CAS 168899-58-9)
- 3-Acetoxy-4-methylbenzoic acid (CAS 17477-46-2)
- 3-(Methoxycarbonyl)-4-methylbenzoic acid (CAS 167300-06-3)
- 3-(Acetoxymethyl)benzoic acid (CAS 174894-86-1)
- (4-Chlorophenyl)(3-(3-((2,4-dichlorobenzyl)oxy)phenyl)-1H-pyrazol-1-yl)methanone (CAS 477712-61-1)
- 5H-Thieno[2,3:5,6][1,3]thiazocino[2,3-a]isoindole-4,11(6aH,13H)-dione 4-(N-phenylhydrazone) (CAS 866008-43-7)
- 5-{[(tert-butoxy)carbonyl]amino}-1,2-oxazole-3-carboxylic acid (CAS 1258503-55-7)
- Adipoyl chloride (CAS 111-50-2)
- 1-(4-methoxyphenyl)-N-methylpiperidin-4-amine (CAS 1096810-46-6)
- 4-(Aminomethyl)-2,2-dimethyltetrahydro-2h-pyran-4-ol (CAS 53979-13-8)
- Diacerein Impurity 15 (CAS CATO-C4X-108115)
- Santicizer® 261 (CAS 68515-40-2)
- 2-Amino-4-morpholin-4-yl-pyrimidine (CAS 861031-56-3)
- Semaglutide impurity 87 (CAS CATO-C4X-222687)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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