N-((6-(Hydroxymethyl)pyridin-2-yl)methyl)acetamide CAS 105243-75-2
| CAS No. | 105243-75-2 |
| Molecular Formula | C9H12N2O2 |
| Molecular Weight | 180.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
N-((6-(Hydroxymethyl)pyridin-2-yl)methyl)acetamide (CAS 105243-75-2) is a high-purity analytical reference standard with the molecular formula C9H12N2O2 and a molecular weight of 180.20 g/mol.
The molecular framework of N-((6-(Hydroxymethyl)pyridin-2-yl)methyl)acetamide (C9H12N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), N-((6-(Hydroxymethyl)pyridin-2-yl)methyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H12N2O2 |
| Molecular Weight | 180.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related N Standards
- (2-(Hydroxymethyl)phenyl)propanoic acid (CAS 10172-25-5)
- methyl 3-(hydroxymethyl)-4-methylbenzoate (CAS 1427432-71-0)
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- 3-(3-(Hydroxymethyl)phenyl)oxetan-3-ol (CAS 1644346-03-1)
- 1-[3-(hydroxymethyl)-4-methoxyphenyl]ethan-1-one (CAS 219539-06-7)
- 3-(4-(Hydroxymethyl)phenyl)propanoic acid (CAS 56703-34-5)
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- Methyl 2-(2-(hydroxymethyl)phenyl)acetate (CAS 63969-91-5)
Recommended Standards
- 2-Amino-5-methoxy-N-methylbenzamide (CAS 104775-68-0)
- 8-Methoxychroman-4-ol (CAS 105329-58-6)
- 2-Amino-4-methoxy-N-methylbenzamide (CAS 104775-67-9)
- 2-[(2-Methoxyphenoxy)methyl]oxirane-d (CAS 1054624-90-6)
- Lycoctonine (CAS 26000-17-9)
- 6-((4-Chlorophenyl)sulfonyl)pyridin-3-amine (CAS 52117-91-6)
- 2-Chloro-4-fluoro-3-(4-fluorophenyl)propiophenone (CAS 898768-62-2)
- 2-Butanone, 4-methoxy-3,3-dimethyl- (9CI) (CAS 80783-13-7)
- 2,3,5-Trifluoro-4-(4-methylpiperazin-1-yl)benzoic acid (CAS 812643-49-5)
- 2-(Chloromethyl)-6-(difluoromethyl)-3-methyl-4-nitropyridine (CAS 1805066-19-6)
- 5-(5-Fluoro-2-hydroxybenzoyl)-1,2-dihydro-2-oxo-1-(2-propen-1-yl)-3-pyridinecarbonitrile (CAS 737820-09-6)
- 2-Bromophenyl carbonochloridate (CAS 89629-87-8)
- 1-(pyridin-2-yl)ethanamine 1-Pyridin-2-yl-ethylamine 42088-91-5 A6888 (CAS 42088-91-5)
- Semaglutide Impurity 8 (CAS CATO-C4X-22268)
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