2-Chloro-4-fluoro-3-(4-fluorophenyl)propiophenone CAS 898768-62-2
| CAS No. | 898768-62-2 |
| Molecular Formula | C15H11ClF2O |
| Molecular Weight | 280.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Chloro-4-fluoro-3-(4-fluorophenyl)propiophenone is closely related to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Chloro-4-fluoro-3-(4-fluorophenyl)propiophenone (CAS 898768-62-2) is a high-purity analytical reference standard with the molecular formula C15H11ClF2O and a molecular weight of 280.70 g/mol.
2-Chloro-4-fluoro-3-(4-fluorophenyl)propiophenone (C15H11ClF2O) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H11ClF2O |
| Molecular Weight | 280.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- Ethyl 3-(6-chloro-2-oxo-2H-chromen-3-yl)propanoate (CAS 1365939-25-8)
- 1-(2-Chloro-4-fluorophenyl)-3-(3-fluorophenyl)propan-1-one (CAS 898767-50-5)
- 1-(3-Chloro-4-fluorophenyl)-3-(3-fluorophenyl)propan-1-one (CAS 898767-29-8)
- 1-(3-Chloro-5-fluorophenyl)-3-(4-fluorophenyl)propan-1-one (CAS 898768-64-4)
- 1-(4-Chloro-2-fluorophenyl)-3-(3-fluorophenyl)propan-1-one (CAS 898767-55-0)
- 1-(4-Chloro-3-fluorophenyl)-3-(4-fluorophenyl)propan-1-one (CAS 898768-46-2)
- 3-(3-Chloro-5-fluorophenyl)-1-(2-fluorophenyl)propan-1-one (CAS 898750-94-2)
- 3-(3-Chloro-5-fluorophenyl)-3-fluoropropiophenone (CAS 898750-58-8)
Recommended Standards
- 3-(3-Chloro-5-fluorophenyl)-4-fluoropropiophenone (CAS 898750-61-3)
- 3-(3-Chlorophenyl)-1-(3,5-difluorophenyl)propan-1-one (CAS 898787-46-7)
- 3-(3-Chlorophenyl)-2,4-difluoropropiophenone (CAS 898787-42-3)
- ethyl 5-(chlorosulfonyl)-4-fluoro-2-methylbenzoate (CAS 1565451-30-0)
- 4-Chloro-6-methyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine (CAS 610279-55-5)
- (Z)-4-chlorobut-2-en-1-amine hydrochloride 7153-66-4 cis-4-Chloro-2-butenylamine hydrochloride (CAS 7153-66-4)
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- (2S,3R,4R,5S,6S)-2-methyl-6-(2,2,2-trichloro-1-iminoethoxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 128571-86-8)
- (Z)-4-(3-Methylisoxazol-5-yl)but-3-en-2-one (CAS 99662-35-8)
- 5-Chloro-2-(4-fluorophenyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1431728-62-9)
- Methyl 6-chloro-5-hydroxypicolinate (CAS 1256808-87-3)
- 2-Amino-1,1,1,7,7,7-hexafluoro-6-hydroxy-2,6-bis(trifluoromethyl)-4-(isopropylimino)heptane (CAS 723294-77-7)
- Tau Peptide (301-315) trifluoroacetate salt (CAS 330456-48-9)
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