4-Amino-3,5-difluoropyridin-2(1H)-one CAS 105252-96-8
| CAS No. | 105252-96-8 |
| Molecular Formula | C5H4F2N2O |
| Molecular Weight | 146.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Amino-3,5-difluoropyridin-2(1H)-one is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Amino-3,5-difluoropyridin-2(1H)-one (CAS 105252-96-8), molecular formula C5H4F2N2O and molecular weight 146.09 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-Amino-3,5-difluoropyridin-2(1H)-one (C5H4F2N2O) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 146.09 g/mol, it falls into the low-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Amino-3,5-difluoropyridin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H4F2N2O |
| Molecular Weight | 146.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 2,5-Difluoro-4-methoxypyrimidine (CAS 123038-80-2)
- Methyl 2-(4-amino-3-benzyl-5-(2-chloroacetyl)-2,6-dioxo-3,6-dihydropyrimidin-1(2h)-yl)acetate (CAS 749219-02-1)
- (3,3-dimethylcyclobutyl)boronic acid (CAS 1950574-55-6)
- (S)-2-Amino-N-((S)-1-benzylpyrrolidin-3-yl)-N-methylpropanamide (CAS 1401666-25-8)
- 10-Hydroxy-2-decenoic acid (CAS 14113-05-4)
- n-Ethoxy-5-iodothiophene-3-carboxamide (CAS 1311991-11-3)
- 4-Bromo-2,2-dimethyl-2-fluorobutyrophenone (CAS 898765-84-9)
- Tri-o-tolyl Phosphite (CAS 2622-08-4)
- IHIC / 4TIC / TTIC (CAS 2127354-15-6)
- (1R,5S)-3-azabicyclo[3.3.1]Nonane-9-carboxylic acid (CAS 1335234-05-3)
- D-[His]1-Semaglutide (CAS CATO-C4X-222652)
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