Ethyl 2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetate CAS 105253-89-2
| CAS No. | 105253-89-2 |
| Molecular Formula | C12H14O4 |
| Molecular Weight | 222.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Ethyl 2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetate (CAS 105253-89-2), molecular formula C12H14O4 and molecular weight 222.24 g/mol, is a CATO reference standard with documented purity and traceability.
Ethyl 2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetate (C12H14O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14O4 |
| Molecular Weight | 222.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
Related Ethyl Standards
- 3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylpropanoic acid (CAS 1017183-14-0)
- 3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)butanoic acid (CAS 1017356-10-3)
- Methyl 2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)propanoate (CAS 1018781-64-0)
- (1-((2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)oxy)cyclopropyl)methanol (CAS 1708251-39-1)
- 2-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)butanoic acid (CAS 18775-55-8)
- N1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-N1-methylethane-1,2-diamine (CAS 1249631-45-5)
- N1-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-N1-methylethane-1,2-diamine (CAS 1249805-62-6)
- N1-((2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)methyl)-N1-methylethane-1,2-diamine (CAS 1353959-17-7)
Recommended Standards
- Methyl (4-propionylphenoxy)acetate (CAS 105253-86-9)
- 5-(2-Methoxyphenyl)-5-oxovaleric acid (CAS 105253-92-7)
- ethyl 2-[(2-carbamoylphenyl)amino]acetate (CAS 105234-33-1)
- 4-(2-Methoxyphenyl)-2-methyl-4-oxobutanoic acid (CAS 105254-01-1)
- 3-(4-Chlorobenzenesulfonyl)-4-methyl-6-phenyl-2-[3-(trifluoromethyl)phenoxy]pyridine (CAS 339103-52-5)
- 3-Bromo-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-6-carbonitrile (CAS 478249-03-5)
- 5-(2-Thiophen-2-yl-quinolin-4-yl)-[1,3,4]oxadiazole-2-thiol (CAS 554423-26-6)
- 2-Chloro-4-methoxybenzene-1,3-diol (CAS 81742-06-5)
- (2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)diphenylphosphine oxide (CAS 445380-60-9)
- (Z)-N'-Hydroxy-[1,1'-biphenyl]-4-carboximidamide (CAS 1648828-03-8)
- 1,3-benzothiazole-6-carbonitrile (CAS 58249-61-9)
- (R)-2-Amino-3-ethylpentanoic acid (CAS 14328-61-1)
- 16:0 Cyanur PE (CAS 1246304-37-9)
- Semaglutide impurity 200 (CAS CATO-C4X-2226200)
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