Paclitaxel EP Impurity E CAS 105454-04-4

Description

Compared with other compounds in its class, the molecular weight of 853.91 g/mol gives Paclitaxel EP Impurity E distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Paclitaxel EP Impurity E (CAS 105454-04-4) is a certified pharmaceutical impurity reference standard with the molecular formula C47H51NO14 and a molecular weight of 853.91 g/mol.

Structurally, Paclitaxel EP Impurity E (C47H51NO14) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 23.0, corresponding to approximately 23 ring(s) or double-bond equivalent(s). With a molecular weight of 853.91 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Why CATO?

• ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
• 130,000+ catalog items in stock, COA supplied with every batch
• Worldwide shipping with full export documentation (HS code guidance available)
• Technical support: +86 18665070610 / Nicole.chen@cato-chem.com