7-Chloro-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one CAS 105544-33-0
| CAS No. | 105544-33-0 |
| Molecular Formula | C7H5ClN2O2 |
| Molecular Weight | 184.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 7-Chloro-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
7-Chloro-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one (CAS 105544-33-0), molecular formula C7H5ClN2O2 and molecular weight 184.58 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 7-Chloro-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 184.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 7-Chloro-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5ClN2O2 |
| Molecular Weight | 184.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-Chloro-6-methoxy-1H-pyrazolo[3,4-d]pyrimidine (CAS 1060816-54-7)
- (6-Chloro-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methanol (CAS 1175301-94-6)
- 4-Chloro-3,7-dihydro-1H-pyrrolo[2,3-b]pyridine-2,6-dione (CAS 1190313-44-0)
- 6-Chloro-4-hydroxy-1H-pyrrolo[2,3-b]pyridin-2(3H)-one (CAS 1190314-80-7)
- 5-Chloro-1H-pyrrolo[2,3-b]pyridine-2,6(3H,7H)-dione (CAS 1190315-19-5)
- 8-CHLORO-1H-PYRIDO[2,3-B][1,4]OXAZIN-2(3H)-ONE (CAS 1198154-62-9)
- 2-Chloro-5-formylbenzoic acid (CAS 1206625-81-1)
- 7-Chloro-2H-pyrido[4,3-b][1,4]oxazin-3(4H)-one (CAS 1206977-63-0)
Recommended Standards
- 1-Chloro-4-ethoxy-1,1-difluorobut-3-en-2-one (CAS 170118-79-3)
- 3-(Chloromethyl)-5-(furan-3-yl)-1,2,4-oxadiazole (CAS 1056157-29-9)
- 1-chloro-4-ethoxy-1,1-difluorobut-3-en-2-one (CAS 131153-94-1)
- PLM4VBZ8MZ 4090-55-5 2-Chloro-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide 1,3,2-Dioxaphosphorinane, 2-chloro-5,5-dimethyl-, 2-oxide EINECS 223-831-2 Phosphorochloridic acid, cyclic (2,2-dimethyltrimethylene) ester UNII-PLM4VBZ8MZ (CAS 4090-55-5)
- 4-(2,5-Dichlorothiophen-3-yl)-4-oxobutanoic acid (CAS 19945-43-8)
- 3-Chloro-2-methoxy-5-(trifluoromethyl)pyridine 1-oxide (CAS 1823188-17-5)
- (2-Amino-4,6-dichloropyrimidin-5-yl)methanol (CAS 850554-81-3)
- METHYL 1-(1-(BENZYLOXYCARBONYL) PYRROLIDIN-3-YL)PIPERIDINE-3-CARBOXYLATE (CAS 1823246-78-1)
- 1,4-Bis(phenylsulfonyl)piperazine (CAS 7250-99-9)
- 2,2,2-Trifluoroethyl (3,4-dichlorophenyl)carbamate (CAS 1736-43-2)
- 7-Chloro-N,N,4-trimethyl-2-oxo-1,2-dihydroquinoline-6-sulfonamide (CAS 1222859-26-8)
- Galactostatin (CAS 107537-94-0)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(4-(trifluoromethoxy)phenyl)butanoic acid (CAS 1260604-66-7)
- CBP501 Affinity Peptide trifluoroacetate salt (CAS 1351804-17-5)
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