| CAS No. | 1056467-54-9 |
| Molecular Formula | C6H10F2O |
| Molecular Weight | 136.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
3,3-Difluoro-1-(2-hydroxyethyl)cyclobutane (CAS 1056467-54-9), molecular formula C6H10F2O and molecular weight 136.14 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3,3-Difluoro-1-(2-hydroxyethyl)cyclobutane (C6H10F2O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3,3-Difluoro-1-(2-hydroxyethyl)cyclobutane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C6H10F2O |
| Molecular Weight | 136.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |