(4-Chloro-3,5-dimethylphenyl)boronic acid CAS 1056475-86-5
| CAS No. | 1056475-86-5 |
| Molecular Formula | C8H10BClO2 |
| Molecular Weight | 184.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(4-Chloro-3,5-dimethylphenyl)boronic acid (CAS 1056475-86-5) is a high-purity analytical reference standard with the molecular formula C8H10BClO2 and a molecular weight of 184.43 g/mol.
Structurally, (4-Chloro-3,5-dimethylphenyl)boronic acid (C8H10BClO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.5, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 184.43 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), (4-Chloro-3,5-dimethylphenyl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10BClO2 |
| Molecular Weight | 184.43 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- (4-Chloro-2,6-dimethylphenyl)boronic acid (CAS 1027045-31-3)
- (4-Chloro-2,5-dimethylphenyl)boronic acid (CAS 1350512-30-9)
- 2-Chloro-5-ethylphenylboronic Acid (CAS 1418023-51-4)
- (2-Chloro-3,5-dimethylphenyl)boronic acid (CAS 1451391-50-6)
- (2-Chloro-4,5-dimethylphenyl)boronic acid (CAS 2246683-46-3)
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- 3-Chloro-2,4-dimethylphenylboronic acid (CAS 2121515-11-3)
Recommended Standards
- (2-(2-Chloroethyl)phenyl)boronic acid (CAS 1238588-10-7)
- 4,5,6-Trichloro-1,2,3-triazine (CAS 70674-51-0)
- 3,5,6-Trichloro-1,2,4-triazine (CAS 873-41-6)
- Cyanuric Chloride (CAS 108-77-0)
- (1-Ethyl-1,3-benzodiazol-5-yl)boronic acid (CAS 1661043-48-6)
- 2-(1,1,1,3,3,3-Hexafluoropropan-2-yloxy)-6-(trifluoromethyl)pyridine (CAS 1707358-17-5)
- tert-Butyl 4-((4-chloro-6-methylpyrimidin-2-yl)oxy)piperidine-1-carboxylate (CAS 1289387-03-6)
- 6-Bromo-2,3-dimethylquinoxaline (CAS 18470-23-0)
- 5-Iodo-3-((trifluoromethyl)thio)pyridin-2-amine (CAS 2386860-18-8)
- Canagliflozin Impurity 100 (CAS CATO-C4X-1123100)
- 4-Amino-3-bromo-2-methoxypyridine (CAS 215364-86-6)
- n-(O-tolyl)ethanethioamide (CAS 10156-36-2)
- ethyl 5-oxooxolane-2-carboxylate (CAS 1126-51-8)
- Semaglutide Impurity 246 (CAS CATO-C4X-2226246)
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