Atrasentan Impurity 98 CAS 1059043-59-2
| CAS No. | 1059043-59-2 |
| Molecular Formula | C37H54N2O6 |
| Molecular Weight | 622.85 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Atrasentan Impurity 98 (CAS 1059043-59-2, C37H54N2O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Atrasentan Impurity 98 (C37H54N2O6) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 622.85 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Atrasentan Impurity 98 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C37H54N2O6 |
| Molecular Weight | 622.85 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
Related Atrasentan Standards
- Atrasentan Impurity 103 (CAS 1059052-06-0)
- Atrasentan Impurity 110 (CAS 1059052-60-6)
- Atrasentan Impurity 141 (CAS 1058349-21-5)
- Atrasentan Impurity 177 (CAS 1059052-00-4)
- Atrasentan Impurity 50 (CAS 1059056-96-0)
- Atrasentan Impurity 53 (CAS 1059057-02-1)
- Atrasentan Impurity 63 (CAS 1140456-19-4)
- Atrasentan Impurity 96 (CAS 1059043-54-7)
Recommended Standards
- Dronedarone Impurity 39 (CAS CATO-C4X-109239)
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- Ginsenoside Rh2 (CAS 78214-33-2)
- Arotinolol Impurity 10 (CAS CATO-C4X-185410)
- Fludarabine Phosphate EP Impurity I (CAS 62314-91-4)
- Carfilzomib Impurity 18 (CAS CATO-C4X-102218)
- Methyl 4-(1-((tert-butoxycarbonyl)amino)-2-hydroxyethyl)benzoate (CAS 156143-81-6)
- Nonyl Chloroformate (CAS 57045-82-6)
- Methyl 2-amino-5-((tetrahydrofuran-3-yl)oxy)benzoate hydrochloride (CAS 2137675-52-4)
- 2-(3-amino-5-bromophenyl)acetic acid hydrochloride (CAS 2060063-86-5)
- 2-((1-Phenylethyl)thio)-1-(phenylsulfonyl)-4,5-dihydro-1H-imidazole (CAS 868216-94-8)
- 2-Methyl-1,3-di(pyridin-4-yl)-2H-isoindole (CAS 24113-74-4)
- Osteoblast-Adhesive Peptide (CAS 193613-75-1)
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