2-Fluoro-N-(thiophen-3-ylmethyl)benzenesulfonamide CAS 1060229-59-5
| CAS No. | 1060229-59-5 |
| Molecular Formula | C11H10FNO2S2 |
| Molecular Weight | 271.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-Fluoro-N-(thiophen-3-ylmethyl)benzenesulfonamide (CAS 1060229-59-5), a certified reference material (molecular formula C11H10FNO2S2, MW 271.33 g/mol) for analytical method development and quality control.
The molecular framework of 2-Fluoro-N-(thiophen-3-ylmethyl)benzenesulfonamide (C11H10FNO2S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 2-Fluoro-N-(thiophen-3-ylmethyl)benzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10FNO2S2 |
| Molecular Weight | 271.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Fluoro Standards
- 3-Fluoro-N-(thiophen-3-ylmethyl)benzenesulfonamide (CAS 1060229-94-8)
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- Methyl 6-[2-fluoro-5-[(E)-prop-1-enyl]phenyl]pyridine-2-carboxylate (CAS 1210419-40-1)
- 4-(3-Fluoro-4-methylphenyl)-4,5-dihydrobenzo[f][1,4]oxazepin-3(2H)-one (CAS 1359410-68-6)
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Recommended Standards
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- Tert-butyl (4S)-4-[(4-fluorophenyl)methyl]-2,2-dioxo-oxathiazolidine-3-carboxylate (CAS 2761225-72-1)
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