6-Chloro-2-(4-chlorophenyl)-3-hydroxyquinazolin-4(3H)-one CAS 106038-62-4
| CAS No. | 106038-62-4 |
| Molecular Formula | C14H8Cl2N2O2 |
| Molecular Weight | 307.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-Chloro-2-(4-chlorophenyl)-3-hydroxyquinazolin-4(3H)-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 6-Chloro-2-(4-chlorophenyl)-3-hydroxyquinazolin-4(3H)-one (CAS 106038-62-4), a certified reference material (molecular formula C14H8Cl2N2O2, MW 307.13 g/mol) for analytical method development and quality control.
Based on its molecular formula C14H8Cl2N2O2, 6-Chloro-2-(4-chlorophenyl)-3-hydroxyquinazolin-4(3H)-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 307.13 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Chloro-2-(4-chlorophenyl)-3-hydroxyquinazolin-4(3H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8Cl2N2O2 |
| Molecular Weight | 307.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 6-Chloro-2-(2-chlorophenyl)-3-hydroxy-3,4-dihydroquinazolin-4-one (CAS 338412-45-6)
- 6-Chloro-2-(3-chlorophenyl)-3-hydroxyquinazolin-4(3H)-one (CAS 338412-46-7)
- 7-Chloro-2-(2-chlorophenyl)-3-hydroxy-3,4-dihydroquinazolin-4-one (CAS 477864-76-9)
- 7-Chloro-2-(4-chlorophenyl)-3-hydroxyquinazolin-4(3H)-one (CAS 477864-77-0)
- 7-Chloro-3-(3-chlorophenyl)quinazoline-2,4(1H,3H)-dione (CAS 61680-22-6)
- 7-Chloro-3-(4-chlorophenyl)quinazoline-2,4(1H,3H)-dione (CAS 61680-20-4)
- 1-(5-Chloro-2-methoxyphenyl)-1h-pyrazole-4-sulfonyl chloride (CAS 1334148-26-3)
- (E)-3-(3-chloro-4-methoxyphenyl)-1-(4-chlorophenyl)prop-2-en-1-one (CAS 861207-58-1)
Recommended Standards
- Azobenzene-4,4'-dicarbonyl Dichloride (CAS 10252-29-6)
- {1-[(tert-butoxy)carbonyl]-6-ethyl-5-fluoro-1h-indol-2-yl}boronicacid (CAS 1248585-73-0)
- 3-(5,7-Dichloro-1H-benzo[d]imidazol-2-yl)benzoic acid (CAS 1024300-63-7)
- 2-(4-Iodo-1h-pyrazol-1-yl)-N-isopropyl-N-methylacetamide (CAS 1339476-09-3)
- Tert-butyl (6-fluoro-1,2,3,4-tetrahydroquinolin-4-yl)carbamate (CAS 1315366-71-2)
- 4-Methyl-1H-pyrrolo[3,2-c]pyridin-3-amine (CAS 1190312-55-0)
- 4-Bromo-5-fluoro-2,3-dihydro-1H-inden-1-amine hydrochloride (CAS 1864056-09-6)
- (S)-2-amino-3-(3,5-dihydroxyphenyl)propanoic acid (CAS 194160-48-0)
- {[(4-Methylphenyl)carbonothioyl]thio}acetic acid (CAS 57149-19-6)
- 2-Methoxy-4-{[(2-methylpropyl)amino]methyl}phenol hydrochloride (CAS 1240568-25-5)
- Tert-butyl 2-sulfamoylacetate (CAS 1178701-12-6)
- Dipentyl succinate (CAS 645-69-2)
- 6,7-Dichloro-2-methylquinolin-4-ol (CAS 948294-27-7)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
Why CATO?
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