6-Chloro-2-(3-chlorophenyl)-3-hydroxyquinazolin-4(3H)-one CAS 338412-46-7
| CAS No. | 338412-46-7 |
| Molecular Formula | C14H8Cl2N2O2 |
| Molecular Weight | 307.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
6-Chloro-2-(3-chlorophenyl)-3-hydroxyquinazolin-4(3H)-one (CAS 338412-46-7), molecular formula C14H8Cl2N2O2 and molecular weight 307.13 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 6-Chloro-2-(3-chlorophenyl)-3-hydroxyquinazolin-4(3H)-one (C14H8Cl2N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 307.13 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 6-Chloro-2-(3-chlorophenyl)-3-hydroxyquinazolin-4(3H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8Cl2N2O2 |
| Molecular Weight | 307.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 6-Chloro-2-(4-chlorophenyl)-3-hydroxyquinazolin-4(3H)-one (CAS 106038-62-4)
- 6-Chloro-2-(2-chlorophenyl)-3-hydroxy-3,4-dihydroquinazolin-4-one (CAS 338412-45-6)
- 7-Chloro-2-(2-chlorophenyl)-3-hydroxy-3,4-dihydroquinazolin-4-one (CAS 477864-76-9)
- 7-Chloro-2-(4-chlorophenyl)-3-hydroxyquinazolin-4(3H)-one (CAS 477864-77-0)
- 7-Chloro-3-(3-chlorophenyl)quinazoline-2,4(1H,3H)-dione (CAS 61680-22-6)
- 7-Chloro-3-(4-chlorophenyl)quinazoline-2,4(1H,3H)-dione (CAS 61680-20-4)
- 1-(5-Chloro-2-methoxyphenyl)-1h-pyrazole-4-sulfonyl chloride (CAS 1334148-26-3)
- (E)-3-(3-chloro-4-methoxyphenyl)-1-(4-chlorophenyl)prop-2-en-1-one (CAS 861207-58-1)
Recommended Standards
- 7-(2,4-Dichlorophenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 338394-73-3)
- 5-[2-(2,4-Dichlorophenoxy)phenyl]-2H-tetrazole (CAS 671186-08-6)
- 4-[2-(4-Iodo-1H-pyrazol-1-yl)ethyl]morpholine (CAS 879488-16-1)
- 4-(3-(2,4-Dichlorophenyl)isoxazol-5-yl)pyrimidin-2-amine (CAS 264256-44-2)
- 1-(tert-Butoxycarbonyl)pyrrolidine-3,4-dicarboxylic acid (CAS 1782350-51-9)
- 3-Bromo-2-fluorobenzofuran-6-carbaldehyde (CAS 648915-98-4)
- 3-Amino-4-(3-(trifluoromethoxy)phenyl)butanoic acid (CAS 1391248-75-1)
- Eribulin Impurity 11 (CAS CATO-C4X-265011)
- 2-(3,4-dimethoxyphenyl)propan-2-amine (CAS 153002-39-2)
- 4-Methylisoquinoline-5-carbonitrile (CAS 1337880-71-3)
- 3-Methoxy-N-(piperidin-4-ylmethyl)quinoxalin-2-amine hydrochloride (CAS 1185313-54-5)
- Relugolix Impurity 21 (CAS CATO-C4X-242921)
- (6-Fluorochroman-2-yl)(piperidin-1-yl)methanone (CAS 878208-57-2)
- D-[Thr]7-Liraglutide (CAS CATO-C4X-199237)
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