4-[(2-Hydroxyethyl)amino]-8-(trifluoromethyl)quinoline CAS 1065076-23-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-[(2-Hydroxyethyl)amino]-8-(trifluoromethyl)quinoline.

CATO supplies 4-[(2-Hydroxyethyl)amino]-8-(trifluoromethyl)quinoline (CAS 1065076-23-4), a certified reference material (molecular formula C12H11F3N2O, MW 256.22 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-[(2-Hydroxyethyl)amino]-8-(trifluoromethyl)quinoline is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 256.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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