3-(2-Chlorophenyl)-2-methyl-5-(trifluoromethyl)quinoxaline CAS 1065482-55-4
| CAS No. | 1065482-55-4 |
| Molecular Formula | C16H10ClF3N2 |
| Molecular Weight | 322.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(2-Chlorophenyl)-2-methyl-5-(trifluoromethyl)quinoxaline (CAS 1065482-55-4) is a high-purity analytical reference standard with the molecular formula C16H10ClF3N2 and a molecular weight of 322.71 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, 3-(2-Chlorophenyl)-2-methyl-5-(trifluoromethyl)quinoxaline is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 322.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(2-Chlorophenyl)-2-methyl-5-(trifluoromethyl)quinoxaline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H10ClF3N2 |
| Molecular Weight | 322.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- (2Z)-2-(4-Chlorophenyl)-3-{[3-(trifluoromethyl)phenyl]amino}prop-2-enenitrile (CAS 338403-10-4)
- 1-(3-Chlorophenyl)-4-(3-(trifluoromethyl)phenyl)-1H-pyrazole (CAS 318288-92-5)
- 5-(4-Chlorophenyl)-1-phenyl-3-(trifluoromethyl)-1H-pyrazole (CAS 586333-28-0)
- 318288-86-7 4-(3-chlorophenyl)-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole KS-000039D1 (CAS 318288-86-7)
- Ethyl 5-(4-chlorophenyl)-4,6-dioxo-3a,5,6,6a-tetrahydro-4H-pyrrolo[3,4-d]isoxazole-3-carboxylate (CAS 338792-98-6)
- (5-((4-Chlorophenyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methanol (CAS 318239-52-0)
- 4-((4-Chlorophenyl)amino)-3-((furan-2-ylmethyl)amino)-4-oxobutanoic acid (CAS 1022917-31-2)
- Ethyl (3-(2-chlorophenyl)-5-methylisoxazole-4-carbonyl)glycinate (CAS 25368-99-4)
Recommended Standards
- 5356-84-3 1,1,1,5,5,5-Hexamethyl-3-((trimethylsilyl)oxy)-3-vinyltrisiloxane Trisiloxane, 3-ethenyl-1,1,1,5,5,5-hexamethyl-3-((trimethylsilyl)oxy)- EINECS 226-342-2 (CAS 5356-84-3)
- 2-(Chloromethyl)-4-(naphthalen-2-yl)-6-(trifluoromethyl)pyrimidine (CAS 1206970-47-9)
- N-[(E)-(5-Chloro-1,3-dimethyl-1H-pyrazol-4-yl)methylidene]-N-[(4-nitrobenzoyl)oxy]amine (CAS 303987-98-6)
- 6-Chloro-4-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2]bipyridinyl-4-carboxylic acid hydrazide (CAS 1208081-12-2)
- 3-chloro-N-[1-(N’-hydroxycarbamimidoyl)-1-methylethyl]benzamide (CAS 1286215-09-5)
- (3AR,4S,6S,7S,7aR)-2,2,6-trimethyl-4-(p-tolylthio)tetrahydro-4H-[1,3]dioxolo[4,5-c]pyran-7-ol (CAS 903906-55-8)
- (2-Chloro-6-nitrophenyl)acetic acid (CAS 31912-08-0)
- S-Thiorphan (CAS 95909-00-5)
- 8-Methyl-3-azabicyclo[3.2.1]octan-8-ol (CAS 1331846-59-3)
- (3'-(Trifluoromethyl)-[1,1'-biphenyl]-2-yl)methanamine (CAS 946714-18-7)
- 3-Bromo-N,N-dimethyl-5-(trifluoromethyl)pyridin-2-amine (CAS 216765-95-6)
- 2-(tert-Butoxy)-4-cyclopropoxy-N,N-dimethylbenzamide (CAS 1243468-67-8)
- (4-Methyl-piperazin-1-yl)-[1,4]oxazepan-6-yl-methanone (CAS 1316227-53-8)
- [2-31]-Semaglutide C (x TFA Salt) (CAS CATO-C4X-2226118)
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