(2Z)-2-(4-Chlorophenyl)-3-{[3-(trifluoromethyl)phenyl]amino}prop-2-enenitrile CAS 338403-10-4
| CAS No. | 338403-10-4 |
| Molecular Formula | C16H10ClF3N2 |
| Molecular Weight | 322.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(2Z)-2-(4-Chlorophenyl)-3-{[3-(trifluoromethyl)phenyl]amino}prop-2-enenitrile (C16H10ClF3N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
(2Z)-2-(4-Chlorophenyl)-3-{[3-(trifluoromethyl)phenyl]amino}prop-2-enenitrile (CAS 338403-10-4) is a high-purity analytical reference standard with the molecular formula C16H10ClF3N2 and a molecular weight of 322.71 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H10ClF3N2 |
| Molecular Weight | 322.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- Ethyl (2S,5S)-5-(5-chloro-2-(trifluoromethyl)pyridin-4-yl)pyrrolidine-2-carboxylate (CAS 1648890-21-4)
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- 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)piperidine-4-carboxylic acid (CAS 1311279-30-7)
- 4-Chloro-2-(difluoro(4-fluorophenyl)methyl)-7-methylquinazoline (CAS 1241915-17-2)
- 1ß-Hydroxytorilin (CAS 509078-16-4)
- Piperazine Related Compound 2 (N-(2-aminoethyl)piperazine-1,4-diethylamine) (CAS 31295-54-2)
- (2-(bromomethyl)-4-fluorophenyl)boronic acid (CAS 850568-01-3)
- Stellettamide A trifluoroacetate (CAS 129744-24-7)
- N-(2,2,2-trifluoro-1-(4-formylpiperazin-1-yl)ethylidene)benzenesulfonamide (CAS 1311319-54-6)
- 6-Methyl-4-isoquinolinol (CAS 1511622-59-5)
- 3-Methoxy-6,7-dihydroisoquinolin-8(5H)-one (CAS 56053-58-8)
- 2-(2-((4-Ethoxyphenyl)amino)thiazol-4-yl)acetic acid (CAS 335398-82-8)
- seco-(8,9)-Buspirone Carboxylic Acid (CAS 257877-46-6)
- Semaglutide impurity 29 (CAS 1188328-22-4)
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