| CAS No. | 1072946-65-6 |
| Molecular Formula | C12H18BF3O3Si |
| Molecular Weight | 306.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
The occurrence of (3-((Tert-butyldimethylsilyl)oxy)-2,4,6-trifluorophenyl)boronic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(3-((Tert-butyldimethylsilyl)oxy)-2,4,6-trifluorophenyl)boronic acid (CAS 1072946-65-6) is a high-purity analytical reference standard with the molecular formula C12H18BF3O3Si and a molecular weight of 306.16 g/mol.
The molecular framework of (3-((Tert-butyldimethylsilyl)oxy)-2,4,6-trifluorophenyl)boronic acid (C12H18BF3O3Si) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (3-((Tert-butyldimethylsilyl)oxy)-2,4,6-trifluorophenyl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C12H18BF3O3Si |
| Molecular Weight | 306.16 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.5 |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |