(3-((Tert-butyldimethylsilyl)oxy)-2,4,6-trifluorophenyl)boronic acid CAS 1072946-65-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1072946-65-6
Molecular FormulaC12H18BF3O3Si
Molecular Weight306.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(3-((Tert-butyldimethylsilyl)oxy)-2,4,6-trifluorophenyl)boronic acid CAS 1072946-65-6 chemical structure

Description

The occurrence of (3-((Tert-butyldimethylsilyl)oxy)-2,4,6-trifluorophenyl)boronic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(3-((Tert-butyldimethylsilyl)oxy)-2,4,6-trifluorophenyl)boronic acid (CAS 1072946-65-6) is a high-purity analytical reference standard with the molecular formula C12H18BF3O3Si and a molecular weight of 306.16 g/mol.

The molecular framework of (3-((Tert-butyldimethylsilyl)oxy)-2,4,6-trifluorophenyl)boronic acid (C12H18BF3O3Si) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (3-((Tert-butyldimethylsilyl)oxy)-2,4,6-trifluorophenyl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H18BF3O3Si
Molecular Weight306.16 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityHygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.5
CAS Registry Year (est.)1988
Halogen ContentF-containing

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