(8-(Trifluoromethyl)quinolin-6-yl)boronic acid CAS 1072951-47-3
| CAS No. | 1072951-47-3 |
| Molecular Formula | C10H7BF3NO2 |
| Molecular Weight | 240.97 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 240.97 g/mol gives (8-(Trifluoromethyl)quinolin-6-yl)boronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies (8-(Trifluoromethyl)quinolin-6-yl)boronic acid (CAS 1072951-47-3), a certified reference material (molecular formula C10H7BF3NO2, MW 240.97 g/mol) for analytical method development and quality control.
(8-(Trifluoromethyl)quinolin-6-yl)boronic acid (C10H7BF3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (8-(Trifluoromethyl)quinolin-6-yl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7BF3NO2 |
| Molecular Weight | 240.97 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- (5-(Trifluoromethyl)quinolin-8-yl)boronic acid (CAS 1072951-55-3)
- 2-Oxo-2-((5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)amino)acetic acid (CAS 1158337-57-5)
- 8-(Trifluoromethyl)quinoline-2-carboxylic acid (CAS 1023815-99-7)
- 6-(Trifluoromethyl)quinoline-4-carboxylic acid (CAS 1092288-36-2)
- 7-(Trifluoromethyl)quinoline-2-carboxylic acid (CAS 1092304-95-4)
- 1-(3-(Trifluoromethyl)phenyl)-1H-1,2,3-triazole-4-carbaldehyde (CAS 113934-28-4)
- 2-(4-(Trifluoromethyl)phenyl)-2H-1,2,3-triazole-4-carbaldehyde (CAS 1202942-42-4)
- 7-(Trifluoromethyl)isoquinoline-3-carboxylic acid (CAS 1256787-80-0)
Recommended Standards
- 1-Bromo-3,3,4,4,4-pentafluoro-2-butanone (CAS 92737-01-4)
- 5-Bromo-2,4-dichloroaniline (CAS 258344-01-3)
- 2,5-Difluoro-4-iodopyridine (CAS 1017793-20-2)
- 5-(Bromomethyl)-2,3-dichloropyridine (CAS 287714-93-6)
- 2-(5-Bromo-2-methoxyphenyl)imidazole (CAS 1369062-98-5)
- 6-Hydrazono-3-(thiophen-2-yl)-1,6-dihydropyridazine (CAS 75792-87-9)
- (3R,7aS)-1,7a-Dihydro-3-phenyl-3H,5H-pyrrolo[1,2-c]oxazol-5-one (CAS 134107-65-6)
- 4-(1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)benzaldehyde (CAS 79421-40-2)
- 4-(1H-Pyrazol-1-yl)thiazole (CAS 123464-70-0)
- 5-[4-(Ethoxycarbonyl) piperidin-1-yl]pyrazine-2-carboxylic acid (CAS 1624301-69-4)
- 2-(4-(Methoxymethyl)phenyl)pyrrolidine (CAS 1493345-06-4)
- 3,5-Dihydroxy-L-Tyrosine (CAS 18674-59-4)
- 1,8-Dibromoisoquinolin-3-amine (CAS 1396762-40-5)
- Semaglutide impurity 75 (CAS CATO-C4X-222675)
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