6-Amino-2-methylthio-4(3H)pyrimidinone CAS 1074-41-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1074-41-5
Molecular FormulaC5H11N3OS
Molecular Weight161.23 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Amino-2-methylthio-4(3H)pyrimidinone CAS 1074-41-5 chemical structure

Description

The occurrence of 6-Amino-2-methylthio-4(3H)pyrimidinone is closely related to an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

6-Amino-2-methylthio-4(3H)pyrimidinone (CAS 1074-41-5), molecular formula C5H11N3OS and molecular weight 161.23 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 6-Amino-2-methylthio-4(3H)pyrimidinone (C5H11N3OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-Amino-2-methylthio-4(3H)pyrimidinone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC5H11N3OS
Molecular Weight161.23 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1957
Nitrogen Atoms3
Sulfur Atoms1

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