8-Fluoroisoquinoline CAS 1075-00-9
| CAS No. | 1075-00-9 |
| Molecular Formula | C9H6FN |
| Molecular Weight | 147.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-Fluoroisoquinoline.
CATO supplies 8-Fluoroisoquinoline (CAS 1075-00-9), a certified reference material (molecular formula C9H6FN, MW 147.15 g/mol) for analytical method development and quality control.
Structurally, 8-Fluoroisoquinoline (C9H6FN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 147.15 g/mol, it falls into the low-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H6FN |
| Molecular Weight | 147.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoroisoquinoline Standards
- 6-Fluoroisoquinoline (CAS 1075-11-2)
- 7-Fluoroisoquinoline (CAS 1075-12-3)
- 1-Fluoroisoquinoline (CAS 394-65-0)
- 3-Fluoroisoquinoline (CAS 396-29-2)
- 4-Fluoroisoquinoline, 97% (CAS 394-67-2)
- 3-Fluoroisoquinoline-1-carbonitrile (CAS 1179148-89-0)
- 5-Fluoroisoquinoline-1-carbonitrile (CAS 1369292-33-0)
- 6-Fluoroisoquinoline-1-carbonitrile (CAS 1427501-46-9)
Recommended Standards
- Methyl (2R,4R)-4-fluoropyrrolidine-2-carboxylate (CAS 1064078-37-0)
- 4-Fluorobicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile (CAS 103447-28-5)
- (2S,4R)-4-Fluoro-1-methylpyrrolidine-2-carboxylic acid (CAS 1007912-97-1)
- 1185166-61-3 Methyl 5-Oxohexanoate-1,4,5-13C3 (CAS 1185166-61-3)
- 1,4-Benzenedicarboxylic acid, polymer with 6-hydroxy-2-naphthalenecarboxylic acid and N-(4-hydroxyphenyl)acetamide, acetate (ester) (CAS 99377-76-1)
- Pyridin-3-ylmethyl-(tetrahydro-furan-2-ylmethyl)-amine hydrobromide (CAS 1185299-21-1)
- N-(Cyanomethyl)-2-((4-ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-phenylacetamide (CAS 852687-58-2)
- (5R)-5-(hydroxymethyl)-1-methylpyrrolidin-2-one (CAS 122663-22-3)
- 3-Bromo-4-chlorobenzohydrazide (CAS 148993-18-4)
- N1-(4-chlorobenzyl)-N4,N4-diethyl-1,4-benzenediamine (CAS 356532-11-1)
- 5-((4-Bromo-3,5-dimethyl-1H-pyrazol-1-yl)methyl)-4-methyl-4H-1,2,4-triazole-3-thiol (CAS 175202-35-4)
- 2-Cyclopentylidenehydrazinecarboximidamide (CAS 4364-76-5)
- 507-16-4 N6CU78B13T Thionyl bromide Thionyl dibromide EINECS 208-064-3 UNII-N6CU78B13T (CAS 507-16-4)
- Hepcidin/LEAP-1 (Human); Liver-Expressed Antimicrobial Peptide (CAS 342790-21-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com