2-Bromo-3,5-difluoro-4-(trimethylsilyl)pyridine CAS 1075756-66-9
| CAS No. | 1075756-66-9 |
| Molecular Formula | C8H10BrF2NSi |
| Molecular Weight | 266.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Bromo-3,5-difluoro-4-(trimethylsilyl)pyridine.
2-Bromo-3,5-difluoro-4-(trimethylsilyl)pyridine (CAS 1075756-66-9), molecular formula C8H10BrF2NSi and molecular weight 266.16 g/mol, is a CATO reference standard with documented purity and traceability.
2-Bromo-3,5-difluoro-4-(trimethylsilyl)pyridine (C8H10BrF2NSi) contains a nitrile group, fluorine/bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Bromo-3,5-difluoro-4-(trimethylsilyl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10BrF2NSi |
| Molecular Weight | 266.16 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 3-bromo-6-methyl-4H-thieno[3,2-b]pyrrole-5-carboxylic acid (CAS 1381776-46-0)
- 5-Bromo-2-(phenylsulfanyl)pyridine (CAS 19520-27-5)
- 3-bromo-4-methyl-thieno[3,2-b]pyrrole-5-carboxylic acid (CAS 2092110-12-6)
- (6-bromo-8-fluoro-3-quinolyl)methanol (CAS 2306262-04-2)
- 7-Bromo-1,2,2,4-tetramethyl-1,2-dihydroquinoline (CAS 1253592-30-1)
- 4-Bromo-2,6-diisopropylbenzonitrile (CAS 1349708-79-7)
- 4-Bromo-3,5-diisopropylbenzonitrile (CAS 2143028-71-9)
- 5'-Bromo-1',2'-dihydrospiro[cyclohexane-1,3'-indole] (CAS 645416-98-4)
Recommended Standards
- (E)-5-Iododec-5-ene (CAS 104293-08-5)
- 3-bromothieno[3,2-b]pyridine-2-carboxylic acid (CAS 1104630-93-4)
- 4,4,5,5-Tetramethyl-2-(4-(methylsulfinyl)phenyl)-1,3,2-dioxaborolane (CAS 1016641-70-5)
- 2,3,4,5,6-Pentafluorobenzyl methacrylate (CAS 114859-23-3)
- 1-(4,6-dichloropyrazolo[3,4-d]pyrimidin-1-yl)-2-methyl-propan-2-ol (CAS 1227062-15-8)
- 3,4-dichlorobenzoyl isothiocyanate (CAS 6954-85-4)
- 2-Fluoro-5-(pyridin-3-yl)benzaldehyde (CAS 1178350-70-3)
- 2,2-Dimethyl-3-(naphthalen-1-yl)-3-oxopropanenitrile (CAS 1893717-41-3)
- F3LB1437XQ 7774-74-5 2-Thiophenethiol Thiophene-2-thiol EINECS 231-881-1 FEMA No. 3062 2-Mercaptothiophene alpha-Thienyl mercaptan 2-Thienyl mercaptan 2-Thienylthiol UNII-F3LB1437XQ (CAS 7774-74-5)
- 3-(3-Fluoro-5-(trifluoromethoxy)phenyl)propanoic acid (CAS 1261828-37-8)
- 2-(4-Ethyl-5-mercapto-4H-[1,2,4]triazol-3-yl)-N-(4-fluoro-phenyl)-acetamide (CAS 792944-74-2)
- 5-(Chloromethyl)salicylaldehyde (CAS 23731-06-8)
- Carulite? Catalyst (CAS 185036-38-8)
- Tirzepatide Impurity 50 (CAS CATO-C4X-324050)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com