5-(Chloromethyl)salicylaldehyde CAS 23731-06-8
| CAS No. | 23731-06-8 |
| Molecular Formula | C8H7ClO2 |
| Molecular Weight | 170.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-(Chloromethyl)salicylaldehyde (C8H7ClO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
5-(Chloromethyl)salicylaldehyde (CAS 23731-06-8), molecular formula C8H7ClO2 and molecular weight 170.59 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(Chloromethyl)salicylaldehyde under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7ClO2 |
| Molecular Weight | 170.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
Related Chloromethyl Standards
- 3-(Chloromethyl)-4-hydroxybenzaldehyde (CAS 53412-47-8)
- Chloromethyl Benzoate (CAS 5335-05-7)
- 6-(Chloromethyl)picolinamide (CAS 1338563-93-1)
- 2-(Chloromethyl)-6-fluoroisonicotinonitrile (CAS 1260897-80-0)
- 4-(Chloromethyl)-6-fluoropicolinonitrile (CAS 1393543-76-4)
- Ethyl (chloromethyl)(Ethyl)phosphinate (CAS 24327-58-0)
- 5-(chloromethyl)-3-cyclopropyl-1-methyl-1H-pyrazole (CAS 1171194-35-6)
- 3-(Chloromethyl)-2-methyl-2,4,5,6-tetrahydrocyclopenta[c]pyrazole (CAS 1251760-95-8)
Recommended Standards
- 4-Methylphenyl chloroformate (CAS 937-62-2)
- 5-Chloro-1,3-dihydroisobenzofuran-1-ol (CAS 98216-82-1)
- 4-Chloro-3-methylbenzoic Acid (CAS 7697-29-2)
- 5-Chloro-2-hydroxy-3-methylbenzaldehyde (CAS 23602-63-3)
- 5-(4-Bromo-1h-pyrazol-1-yl)-1h-tetrazole (CAS 496918-93-5)
- 1-Boc-4-(2-chloro-6-nitrophenyl)piperazine (CAS 400803-05-6)
- tert-Butyl (1-cyano-3-methylbutyl)carbamate (CAS 774225-54-6)
- 4-Chloro-2-(3,4-dimethoxyphenyl)quinazoline (CAS 1518833-18-5)
- 1-{4-[(4-Chlorobenzyl)oxy]phenyl}ethanone (CAS 61035-74-3)
- Dimethyl thiazolidine-2,4-dicarboxylate (CAS 318233-97-5)
- (5-(Benzyloxy)-2-methylphenyl)methanol (CAS 1450931-37-9)
- 5-Bromo-3H-spiro[benzofuran-2,4'-piperidine] (CAS 91830-17-0)
- 4-[5-(4-Methoxy-phenoxymethyl)-4-methyl-thiazol-2-yl]-azepan-4-ol hydrochloride (CAS 1361111-67-2)
- Semaglutide impurity 249 (CAS CATO-C4X-2226249)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com