4-Nitronicotinic acid N-oxide CAS 1078-05-3
| CAS No. | 1078-05-3 |
| Molecular Formula | C6H4N2O5 |
| Molecular Weight | 184.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Nitronicotinic acid N-oxide (C6H4N2O5) is characterized by a carbohydrate-derived structure, an amide group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 4-Nitronicotinic acid N-oxide (CAS 1078-05-3), a certified reference material (molecular formula C6H4N2O5, MW 184.11 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H4N2O5 |
| Molecular Weight | 184.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Nitronicotinic Standards
Recommended Standards
- 3-Nitro-1,4-dihydro-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4-ol (CAS 107753-06-0)
- 2-Hydroxypyrimidine-4,6-dicarboxylic acid (CAS 114832-74-5)
- Chelidonic acid (CAS 99-32-1)
- 3-Hydroxy-3-(trifluoromethyl)cyclobutanecarboxylic acid (CAS 1163729-49-4)
- 4-chloro-2,3-difluoro-pyridine (CAS 851178-99-9)
- ε-Caprolactam-d10 (CAS 169297-53-4)
- [(3-Methylphenyl)methyl](propyl)amine hydrochloride (CAS 16065-30-8)
- 3-(3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl)propan-1-amine hydrochloride (CAS 1374407-72-3)
- Dipyrrolidinylthiuram Disulfide (CAS 496-08-2)
- 2,6-Diamino-5-(3,4-dichlorophenyl)pyrimidine-4-carbaldehyde (CAS 20535-54-0)
- (S)-2-((3-Sulfopropyl)amino)propanoic acid (CAS 819863-37-1)
- 1-Chloro-2-Iodo-1,1,2-Trifluoroethane (CAS 354-26-7)
- Ethyl 3-phenyl-5-(trifluoromethyl)isoxazole-4-carboxylate, 97% (CAS 157951-16-1)
- Semaglutide impurity 233 (CAS CATO-C4X-2226233)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com