3',4'-Difluoro-[1,1'-biphenyl]-4-ol CAS 108185-80-4
| CAS No. | 108185-80-4 |
| Molecular Formula | C12H8F2O |
| Molecular Weight | 206.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3',4'-Difluoro-[1,1'-biphenyl]-4-ol (CAS 108185-80-4), molecular formula C12H8F2O and molecular weight 206.19 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3',4'-Difluoro-[1,1'-biphenyl]-4-ol (C12H8F2O) contains a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 206.19 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H8F2O |
| Molecular Weight | 206.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 2,4-Difluoro-3-(pyridin-4-yl)aniline (CAS 100325-60-8)
- 3',4'-Difluoro-[1,1'-biphenyl]-3-ol (CAS 1027207-72-2)
- 2',4-Difluoro-[1,1'-biphenyl]-3-ol (CAS 1214341-66-8)
- 2',5-Difluoro-[1,1'-biphenyl]-3-ol (CAS 1214345-59-1)
- 4,4'-Difluoro-[1,1'-biphenyl]-3-ol (CAS 1214367-64-2)
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Recommended Standards
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- 4,6,6-Trimethyloxepan-2-one (CAS 2549-57-7)
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- (3-Fluoro-2-methoxy-5-(methylthio)phenyl)boronic acid (CAS 957065-83-7)
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