LCZ696杂质585-11 CAS 1082985-24-7
| CAS No. | 1082985-24-7 |
| Molecular Formula | C18H21NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies LCZ696杂质585-11 (CAS 1082985-24-7), a pharmacopoeial impurity reference standard (molecular formula C18H21NO2HCl, MW 319.83 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C18H21NO2HCl, LCZ696杂质585-11 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 319.83 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), LCZ696杂质585-11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H21NO2 HCl |
| Molecular Weight | 319.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Cholic Acid Impurity 28 (CAS CATO-C4X-116028)
- 7-ACA Impurity 2 (CAS 18884-65-6)
- Zanamivir EP Impurity C (CAS 130525-62-1)
- 2,2,2-Trifluoro-N-phenethylacetamide (CAS 458-85-5)
- Rubimaillin (CAS 55481-88-4)
- Rosuvastatin Impurity 266 (CAS 775571-58-9)
- 2-Bromo-1,8-diisopropoxy-3-methylanthracene-9,10-dione (CAS 919114-38-8)
- 1-(2-Chlorophenyl)-N-methyl-3-(pyrrolidin-1-yl)propan-1-aminehydrochloride (CAS 1956335-24-2)
- 3-Bromoimidazo[1,2-a]pyrazine-6-carboxylic acid (CAS 1234015-04-3)
- Semaglutide Impurity 158 (x TFA Salt) (CAS CATO-C4X-2226158)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com