3-(3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylic acid CAS 108446-72-6
| CAS No. | 108446-72-6 |
| Molecular Formula | C18H13FN2O2 |
| Molecular Weight | 308.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 3-(3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies 3-(3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylic acid (CAS 108446-72-6), a certified reference material (molecular formula C18H13FN2O2, MW 308.31 g/mol) for analytical method development and quality control.
3-(3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylic acid (C18H13FN2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H13FN2O2 |
| Molecular Weight | 308.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorophenyl Standards
- (2e)-3-[3-(4-fluorophenyl)-1-phenyl-1h-pyrazol-4-yl]prop-2-enoic acid (CAS 519137-39-4)
- 4-(2-Fluorophenyl)-3-methyl-3,4-dihydro-1H-indeno[1,2-d]pyrimidine-2,5-dione (CAS 861212-93-3)
- 2-(4-Fluorophenyl)-2-oxoethyl 4-methylbenzenesulfonate (CAS 357952-79-5)
- N'-(4-fluorophenyl)-N-formyl-4-methylbenzenesulfonohydrazide (CAS 1513-05-9)
- 1-(4-Fluorophenyl)-6-oxo-4-(propylsulfanyl)-1,6-dihydro-3-pyridazinecarboxylic acid (CAS 339096-33-2)
- Ethyl 1-(4-fluorophenyl)-2-(methylthio)-6-oxo-1,6-dihydropyrimidine-5-carboxylate (CAS 82636-14-4)
- N-((3-fluorophenyl)carbamoyl)-4-methylbenzenesulfonamide (CAS 349422-81-7)
- 1-(4-Fluorophenyl)-4-isopropyl-2-phenyl-1H-imidazole-5-carbaldehyde (CAS 109083-75-2)
Recommended Standards
- [(3-carbamoylthiophen-2-yl)carbamoyl]methyl 3-methylfuran-2-carboxylate (CAS 1060777-62-9)
- 1219707-39-7 43EP6XV33E LCB01-0371 UNII-43EP6XV33E (5R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-one (5R)-3-(3-Fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one 2-Oxazolidinone, 3-(4-(5,6-dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl)-5-(hydroxymethyl)-, (5R)- LCB-010371 LCB-01-0371 (CAS 1219707-39-7)
- N-(4-Methoxyphenyl)-4-nitrobenzenesulfonamide (CAS 10553-17-0)
- 6-(4-Methoxyphenylsulfonamido)nicotinic acid (CAS 1272758-14-1)
- 11H-DIBENZO[B,E][1,4]DIAZEPIN-11-ONE, 2-BROMO-5,10-DIHYDRO- (CAS 949570-72-3)
- 5-Bromo-4-(trifluoromethyl)pyrimidin-2(1H)-one (CAS 785777-90-4)
- (1,2-Dimethylazetidin-2-yl)methanol hydrochloride (CAS 2288710-13-2)
- 1-Chloro-3-(difluoromethyl)-2-ethylbenzene (CAS 2384619-73-0)
- 7-(4-Bromophenyl)-2-chloro-6-(4-methoxyphenyl)-7,12-dihydro-6H-chromeno[4,3-d][1,2,4]triazolo[1,5-a]pyrimidine (CAS 303094-16-8)
- (S)-2-((S)-1-(4-bromophenyl)-2,2,2-trifluoroethylamino)-4-fluoro-4-methylpentanoic acid (CAS 847358-98-9)
- (3-Bromo-2,6-dichlorophenyl)methanol (CAS 1807171-96-5)
- Tandospirone Impurity 9 (CAS 541-59-3)
- Methyl 4-methylpiperidine-2-carboxylate (CAS 144817-80-1)
- Insulin Degludec Impurity 12 (CAS CATO-C4X-215712)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com